Ammonium phenoxides-catalyzed syn-selective aldol reaction between an aldehyde and an trimethylsilyl enolate

被引：10
|
作者：
Fujisawa, H
Nagata, Y
Sato, Y
Mukaiyama, T
机构：
[1] Kitasato Inst TCI, Ctr Basic Res, Kita Ku, Tokyo 1140003, Japan
[2] Kitasato Univ, Kitasato Inst Life Sci, Minato Ku, Tokyo 1088641, Japan
来源：
CHEMISTRY LETTERS | 2005年 / 34卷 / 06期
关键词：
D O I：
10.1246/cl.2005.842
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Aldol reactions between aldehydes and trimethylsilyl enolates generated from ketones or thioesters proceeded smoothly in the presence of a Lewis base catalyst such as tetrabutylammonium phenoxide or p-methoxyphenoxide in THF to afford the corresponding aldols in high yields with high syn-selectivity.
引用
收藏
页码：842 / 843
页数：2
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