Renal cell carcinoma associated with TFE3 gene fusion in an elderly woman

被引:13
作者
LaGrange, Chad A. [1 ]
Lele, Subodh M. [1 ]
Strup, Stephen E. [1 ]
机构
[1] Univ Kentucky, Div Urol & Pathol, Dept Surg, Lexington, KY 40536 USA
关键词
D O I
10.1016/j.urology.2007.06.1096
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
We present a case report of a renal cell carcinoma with TFE3 overexpression (related to TFE3 gene fusion) in a 63-year-old woman. Such tumors have been reported predominantly in children and young adults, and to our knowledge there are only 2 such cases mentioned in the literature in patients older than ours. However, we believe that this tumor may be underdiagnosed in adults owing to its similarity to clear cell (conventional) carcinoma and in some cases to papillary renal carcinoma.
引用
收藏
页码:590.e11 / 590.e12
页数:2
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