Orthodontically induced root resorption in rat molars after 1-hydroxyethylidene-1,1-bisphosphonate injection

被引:21
作者
Alatli, I
Hellsing, E
Hammarstrom, L
机构
[1] KAROLINSKA INST, FAC ODONTOL, DEPT ORAL PATHOL, S-14104 HUDDINGE, SWEDEN
[2] KAROLINSKA INST, FAC ODONTOL, DEPT ORTHODONT, S-14104 HUDDINGE, SWEDEN
关键词
dental cementum; orthodontics; tooth root;
D O I
10.3109/00016359609006013
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
single injection of 1-hydroxyethylidene-1,1-bisphosphonate inhibits the formation of acellular cementum in rat molars. Instead, an atypical hyperplastic cementum is formed. In this study the resistance of this cementum to resorption was tested by applying an orthodontic force. It was found that roots lacking acellular cementum were readily resorbed. The readiness with which the atypical hyperplastic cementum was resorbed without any increase in multinucleated osteoblasts may offer useful opportunities to study the different phases of hard-tissue resorption.
引用
收藏
页码:102 / 108
页数:7
相关论文
共 26 条
[1]  
ALATLIKUT I, 1994, SCAND J DENT RES, V102, P260
[2]   EFFECTS OF 1-HYDROXYETHYLIDENE-1, 1-BISPHOSPHONATE (HEBP) ON THE FORMATION OF DENTIN AND THE PERIODONTAL ATTACHMENT APPARATUS IN THE MOUSE [J].
BEERTSEN, W ;
NIEHOF, A ;
EVERTS, V .
AMERICAN JOURNAL OF ANATOMY, 1985, 174 (01) :83-103
[3]   ROOT RESORPTION AFTER ORTHODONTIC TREATMENT .2. LITERATURE-REVIEW [J].
BREZNIAK, N ;
WASSERSTEIN, A .
AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS, 1993, 103 (02) :138-146
[4]   ROOT RESORPTION BENEATH THE MAIN HYALINIZED ZONE [J].
BRUDVIK, P ;
RYGH, P .
EUROPEAN JOURNAL OF ORTHODONTICS, 1994, 16 (04) :249-263
[5]  
FLEISCH H, 1993, OSTEOPOROSIS INT, V3, pS3
[6]   ROOT RESORPTION AND TOOTH MOVEMENT IN ORTHODONTICALLY TREATED, CALCIUM-DEFICIENT, AND LACTATING RATS [J].
GOLDIE, RS ;
KING, GJ .
AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS, 1984, 85 (05) :424-430
[7]  
Hammarstrom L, 1992, Proc Finn Dent Soc, V88 Suppl 1, P115
[8]   THE EFFECTS OF PREGNANCY AND FLUORIDE ON ORTHODONTIC TOOTH MOVEMENTS IN RATS [J].
HELLSING, E ;
HAMMARSTROM, L .
EUROPEAN JOURNAL OF ORTHODONTICS, 1991, 13 (03) :223-230
[9]  
HELLSING E, 1994, IN PRESS EUR J ORTHO
[10]   SCANNING ELECTRON-MICROSCOPY OF TISSUE CHANGES ON PRESSURE SURFACE OF HUMAN PREMOLARS FOLLOWING TOOTH MOVEMENT [J].
KVAM, E .
SCANDINAVIAN JOURNAL OF DENTAL RESEARCH, 1972, 80 (05) :357-+