SARS-CoV-2 seroprevalence in the city of Hyderabad, India in early

被引:3
作者
Laxmaiah, Avula [1 ]
Rao, Nalam Madhusudhan [2 ]
Arlappa, N. [1 ]
Babu, Jagjeevan [1 ]
Kumar, P. Uday [1 ]
Singh, Priya [2 ]
Sharma, Deepak [2 ]
Anumalla, V. Mahesh [2 ]
Kumar, T. Santhosh [2 ]
Sabarinathan, R. [3 ]
Kumar, M. Santhos [3 ]
Ananthan, R. [1 ]
Basha, D. Anwar [1 ]
Blessy, P. P. S. [1 ]
Kumar, D. Chandra [1 ]
Devaraj, P. [1 ]
Devendra, S. [1 ]
Kumar, M. Mahesh [1 ]
Meshram, Indrapal I. [1 ]
Kumar, B. Naveen [1 ]
Sharma, Paras [1 ]
Raghavendra, P. [1 ]
Raghu, P. [1 ]
Rao, K. Rajender [1 ]
Ravindranadh, P. [1 ]
Kumar, B. Santosh [1 ]
Sarika, G. [1 ]
Rao, J. Srinivasa [1 ]
Surekha, M. V. [1 ]
Sylvia, F. [1 ]
Kumar, Deepak [1 ]
Rao, G. Subba [1 ]
Tallapaka, Karthik Bharadwaj [2 ]
Sowpati, Divya Tej [2 ]
Srivastava, Surabhi [2 ]
Murhekar, V. Manoj [3 ]
Hemalatha, Rajkumar [1 ]
Mishra, Rakesh K. [2 ]
机构
[1] ICMR Natl Inst Nutr, Hyderabad, Telangana, India
[2] CSIR Ctr Cellular & Mol Biol, Hyderabad, Telangana, India
[3] ICMR Natl Inst Epidemiol, Chennai, Tamil Nadu, India
来源
IJID REGIONS | 2022年 / 2卷
关键词
COVID-19; India; Hyderabad; SARS-CoV-2; antibody; seroprevalence; serosurveillance; POPULATION; SEROSURVEY;
D O I
10.1016/j.ijregi.2021.10.009
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Background: COVID-19 emerged as a global pandemic in 2020, spreading rapidly to most parts of the world. The proportion of infected individuals in a population can be reliably estimated via serosurveillance, making it a valuable tool for planning control measures. Our serosurvey study aimed to investigate SARS-CoV-2 seroprevalence in the urban population of Hyderabad at the end of the first wave of infections. Methods: This cross-sectional survey, conducted in January 2021 and including males and females aged 10 years and above, used multi-stage random sampling. 9363 samples were collected from 30 wards distributed over six zones of Hyderabad, and tested for antibodies against SARS-CoV-2 nucleocapsid antigen. Results: Overall seropositivity was 54.2%, ranging from 50% to 60% in most wards. Highest exposure appeared to be among those aged 30-39 and 50-59 years, with women showing greater seropositivity. Seropositivity increased with family size, with only marginal differences among people with varying levels of education. Seroprevalence was significantly lower among smokers. Only 11% of the survey subjects reported any COVID-19 symptoms, while 17% had appeared for COVID-19 testing. Conclusion: Over half the city's population was infected within a year of onset of the pandemic. However, - 46% of people remained susceptible, contributing to subsequent waves of infection.
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页码:1 / 7
页数:7
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