Hyaluronic Acid and Chondroitin Sulphate Treatment for Recurrent Severe Urinary Tract Infections due to Multidrug-Resistant Gram-Negative Bacilli in a Patient With Multiple Sclerosis: Case Report and Literature Review

被引：5

作者：

Dinh, Aurelien ^{[1
]}

Duran, Clara ^{[1
]}

Hamami, Kamel ^{[2
]}

Afif, Muriel ^{[2
]}

Bonnet, Francine ^{[3
]}

Donay, Jean-Luc ^{[4
]}

Lafaurie, Matthieu ^{[5
]}

Chartier-Kastler, Emmanuel ^{[6
]}

机构：

[1] Paris Saclay Univ, Raymond Poincare Univ Hosp, AP HP, Infect Dis Dept, 104 Bd Raymond Poincare, F-92380 Garches, France

[2] Paris Saclay Univ, Raymond Poincare Univ Hosp, AP HP, Pharm, Garches, France

[3] Univ Paris, St Louis Univ Hosp, AP HP, Anesthesiol Dept, Paris, France

[4] Univ Paris, St Louis Univ Hosp, AP HP, Microbiol Dept, Paris, France

[5] Univ Paris, St Louis Univ Hosp, AP HP, Infect Dis Dept, Paris, France

[6] Paris Sorbonne Univ, Pitie Salpetriere Univ Hosp, AP HP, Urol Dept, Paris, France

来源：

OPEN FORUM INFECTIOUS DISEASES | 2022年 / 9卷 / 07期

关键词：

antibiotics; hyaluronic acid; MDRO; neurogenic bladder; urinary tract infection; BACTERIAL CYSTITIS; INTRAVESICAL INSTILLATION; ACID/CHONDROITIN SULFATE; PREVENTION; THERAPY;

D O I：

10.1093/ofid/ofac245

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Urinary tract infections (UTIs) are the most common bacterial infections in patients with neurogenic lower urinary tract dysfunction. Antibiotic options for prophylaxis or curative treatment in case of recurrent UTIs, especially due to multidrug-resistant organisms (MDRO), are scarce. We present the case of a 72-year-old man with neurogenic lower urinary tract dysfunction and history of frequent recurrent UTIs due to multiple MDROs who was successfully treated with hyaluronic acid (HA) and chondroitin sulfate (CS) bladder instillations. We also provide a literature review on the efficacy of HA-CS intravesical instillations for prevention of UTI among this population.

引用

页数：4

共 21 条

[1] Intravesical administration of combined hyaluronic acid (HA) and chondroitin sulfate (CS) for the treatment of female recurrent urinary tract infections: a European multicentre nested case-control study [J].

Ciani, Oriana ;

Arendsen, Erik ;

Romancik, Martin ;

Lunik, Richard ;

Costantini, Elisabetta ;

Di Biase, Manuel ;

Morgia, Giuseppe ;

Fragala, Eugenia ;

Roman, Tomaskin ;

Bernat, Marian ;

Guazzoni, Giorgio ;

Tarricone, Rosanna ;

Lazzeri, Massimo .

BMJ OPEN, 2016, 6 (03)

[2] Intravesical treatment with highly-concentrated hyaluronic acid and chondroitin sulphate in patients with recurrent urinary tract infections: Results from a multicentre survey [J].

Cicione, Antonio ;

Cantiello, Francesco ;

Ucciero, Giuseppe ;

Salonia, Andrea ;

Torella, Marco ;

De Sio, Marco ;

Autorino, Riccardo ;

Carbone, Antonio ;

Romancik, Martin ;

Tomaskin, Roman ;

Damiano, Rocco .

CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL, 2014, 8 (9-10) :E721-E727

[3] Prevention of recurrent bacterial cystitis by intravesical administration of hyaluronic acid: a pilot study [J].

Constantinides, C ;

Manousakas, T ;

Nikolopoulos, P ;

Stanitsas, A ;

Haritopoulos, K ;

Giannopoulos, A .

BJU INTERNATIONAL, 2004, 93 (09) :1262-1266

[4] Morphological Changes of Bladder Mucosa in Patients Who Underwent Instillation with Combined Sodium Hyaluronic Acid-Chondroitin Sulphate (Ialuril®) [J].

Costantini, E. ;

Lazzeri, M. ;

Pistolesi, D. ;

Del Zingaro, M. ;

Frumenzio, E. ;

Boni, A. ;

Pietropaolo, A. ;

Fragala, E. ;

Porena, M. .

UROLOGIA INTERNATIONALIS, 2013, 91 (01) :81-88

[5] Prevention of Recurrent Urinary Tract Infections by Intravesical Administration of Hyaluronic Acid and Chondroitin Sulphate: A Placebo-Controlled Randomised Trial [J].

Damiano, Rocco ;

Quarto, Giuseppe ;

Bava, Ilaria ;

Ucciero, Giuseppe ;

De Domenico, Renato ;

Palumbo, Michele I. ;

Autorino, Riccardo .

EUROPEAN UROLOGY, 2011, 59 (04) :645-651

[6] Bacterial Interference for Prevention of Urinary Tract Infection [J].

Darouiche, Rabih O. ;

Hull, Richard A. .

CLINICAL INFECTIOUS DISEASES, 2012, 55 (10) :1400-1407

[7] Long-term efficacy of intravesical instillation of hyaluronic acid/chondroitin sulfate in recurrent bacterial cystitis: 36 months' follow-up [J].

De Vita, D. ;

Madonia, M. ;

Coppola, E. ;

Sciorio, C. ;

Giordano, S. ;

Dessole, S. ;

Capobianco, G. .

CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY, 2018, 45 (02) :224-228

[8] Effectiveness of intravesical hyaluronic acid/chondroitin sulfate in recurrent bacterial cystitis: a randomized study [J].

De Vita, Davide ;

Giordano, Salvatore .

INTERNATIONAL UROGYNECOLOGY JOURNAL, 2012, 23 (12) :1707-1713

[9] Blood stream infections due to multidrug-resistant organisms among spinal cord-injured patients, epidemiology over 16 years and associated risks: a comparative study [J].

Dinh, A. ;

Saliba, M. ;

Saadeh, D. ;

Bouchand, F. ;

Descatha, A. ;

Roux, A. L. ;

Davido, B. ;

Clair, B. ;

Denys, P. ;

Annane, D. ;

Perronne, C. ;

Bernard, L. .

SPINAL CORD, 2016, 54 (09) :720-725

[10] Weekly Sequential Antibioprophylaxis for Recurrent Urinary Tract Infections Among Patients With Neurogenic Bladder: A Randomized Controlled Trial [J].

Dinh, Aurelien ;

Hallouin-Bernard, Marie-Charlotte ;

Davido, Benjamin ;

Lemaignen, Adrien ;

Bouchand, Frederique ;

Duran, Clara ;

Even, Alexia ;

Denys, Pierre ;

Perrouin-Verbe, Brigitte ;

Sotto, Albert ;

Lavigne, Jean-Philippe ;

Bruyere, Franck ;

Grall, Nathalie ;

Tavernier, Elsa ;

Bernard, Louis .

CLINICAL INFECTIOUS DISEASES, 2020, 71 (12) :3128-3135

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