Bionanoprobes with Excellent Two-Photon-Sensitized Eu3+ Luminescence Properties for Live Cell Imaging

被引：49
作者：
Shao, Guangsheng [1 ]
Han, Rongcheng [1 ]
Ma, Yan [1 ]
Tang, Minxian [1 ]
Xue, Fumin [1 ]
Sha, Yinlin [2 ,3 ]
Wang, Yuan [1 ]
机构：
[1] Peking Univ, Coll Chem & Mol Engn, State Key Lab Struct Chem Unstable & Stable Speci, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China
[2] Peking Univ, Dept Biophys, Sch Basic Med Sci, Beijing 100191, Peoples R China
[3] Peking Univ, Biomed X Ctr, Beijing 100191, Peoples R China
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2010年 / 16卷 / 29期
关键词：
bioimaging; europium; imaging agents; luminescence; nanoparticles; EUROPIUM COMPLEX; CROSS-SECTIONS; NANOPARTICLES;
D O I：
10.1002/chem.201001367
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Bionanoprobes with high dispersion stability in water, excellent photostability, and biocompatibility were prepared by encapsulating [Eu(tta)3dpbt] (tta = thenoyltrifluoroacetonato, dpbt = 2-(N,N-diethylanilin-4-yl)-4,6-bis-(3,5-dimethylpyrazol-1 -yl)-1,3,5-triazine) in water-dispersible poly(methyl methacrylate-co-methacrylic acid) nanospheres and modifying the nanosphere surfaces with a monoclonal antibody (see scheme). The bionanoprobes exhibited excellent performance in the target-specific imaging of live cancer cells. (Figure Presented) © 2010 Wiley-VCH Verlag GmbH&Co. KGaA, Weinheim.
引用
收藏
页码：8647 / 8651
页数：5
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