Protein adhesion at poly(ethylene glycol) modified surface

被引：0
|
作者：
Snellings, GMBF
Vansteenkiste, SO
Corneillie, SI
Davies, MC
Schacht, EH
机构：
[1] State Univ Ghent, Dept Organ Chem, Polymer Mat Res Grp, B-9000 Ghent, Belgium
[2] Univ Nottingham, Dept Pharmaceut Sci, Nottingham NG7 2RD, England
来源：
ADVANCED MATERIALS | 2000年 / 12卷 / 24期
关键词：
D O I：
10.1002/1521-4095(200012)12:24<1959::AID-ADMA1959>3.3.CO;2-M
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The inhibition of protein adsorption to the surfaces of biomedical devices is a crucial requirement for avoiding implant-associated infections or thrombus formation on blood-contacting artificial surfaces and thus for increasing the long-term biocompatibility of the devices. Here, the use of surface plasmon resonance and scanning force microscopy using protein-modified tips (see Figure) to study protein adhesion on poly (ethylene glycol) grafted polymer materials is discussed. The PEG-grafted materials are revealed to have significantly reduced affinity to proteins.
引用
收藏
页码：1959 / +
页数：5
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