Acquired ichthyosis associated with chronic graft-versus-host disease following allogeneic peripheral blood stem cell transplantation in a patient with chronic myelogenous leukemia

被引：15

作者：

Dilek, I

Demirer, T ^{[1
]}

Üstün, C

Arat, M

Koç, H

Beksaç, M

Erdi, H

Anadolu, R

Özcan, M

Ilhan, O

Akan, H

机构：

[1] Ankara Univ, Sch Med, Ibni Sina Hosp, Dept Hematol Oncol, TR-06100 Ankara, Turkey

[2] Ankara Univ, Sch Med, Ibni Sina Hosp, Bone Marrow Transplant Unit, TR-06100 Ankara, Turkey

[3] Ankara Univ, Sch Med, Ibni Sina Hosp, Dept Dermatol, TR-06100 Ankara, Turkey

来源：

BONE MARROW TRANSPLANTATION | 1998年 / 21卷 / 11期

关键词：

acquired ichthyosis; chronic graft-versus-host disease; allogeneic peripheral blood stem cell transplantation;

D O I：

10.1038/sj.bmt.1701240

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Acquired ichthyosis (AI) has rarely been described following bone marrow transplantation (BMT). We report a 29-year-old male, who underwent allogeneic peripheral blood stem cell transplantation (alloPBSCT) for chronic myelogenous leukemia, and who developed AI associated with chronic graft-versus-host disease (cGVHD). Both of these disorders were treated successfully with cyclosporin A. We conclude that AI may be related to an autoimmune process on the basis of cGVHD, and dermathopathologic evaluation must be performed in patients with skin changes suggesting AI following allogeneic bone marrow transplantation.

引用

页码：1159 / 1161

页数：3

共 9 条

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[2]

BREN CA, 1986, ARCH DERMATOL, V122, P1028

[3]

Devriendt K, 1996, AM J MED GENET, V61, P127

[4] ACQUIRED ICHTHYOSIS - MULTIPLE CAUSES FOR AN ACQUIRED GENERALIZED DISTURBANCE IN DESQUAMATION [J].