Length of stay prediction for ICU patients using individualized single classification algorithm

被引:41
|
作者
Ma, Xin [1 ]
Si, Yabin [1 ]
Wang, Zifan [1 ]
Wang, Youqing [1 ,2 ]
机构
[1] Beijing Univ Chem Technol, Beijing, Peoples R China
[2] Shandong Univ Sci & Technol, Qingdao, Shandong, Peoples R China
基金
美国国家科学基金会; 中国国家自然科学基金;
关键词
Length of stay (LOS); ICU patients; Personalized diagnosis; Just in time learning (JITL); Extreme learning machine (ELM); Two-step principal component analysis (TS-PCA); MORTALITY; SYSTEM; MODEL;
D O I
10.1016/j.cmpb.2019.105224
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Background and Objective: In intensive care units (ICUs), length of stay (LOS) prediction is critical to help doctors and nurses select appropriate treatment options and predict patients' condition. Considering that most hospitals use universal models to predict patients' condition, which cannot meet the individual needs of special ICU patients. Our goal is to create a personalized model for patients to determine the number of hospital stays. Methods: In this study, a new combination of just-in-time learning (JITL) and one-class extreme learning machine (one-class ELM) is proposed to predict the number of days a patient stays in hospital. This combination is shortened as one-class JITL-ELM, where JITL is used to search for personalized cases for a new patient and one-class ELM is used to determine whether the patient can be discharged within 10 days. Results: The experimental results show that the one-class JITL-ELM model has an area under the curve (AUC) index of 0.8510, lift value of 2.1390, precision of 1, and G-mean is 0.7842. Its accuracy, specificity, and sensitivity were found as 0.82, 1, and 0.6150, respectively. Moreover, a novel simple mortality risk level estimation system that can determine the mortality rate of a patient by combining LOS and age is proposed. It has an accuracy rate of 66% and the miss rate of only 6.25%. Conclusions: Overall, the one-class JITL-ELM can accurately predict hospitalization days and mortality using early physiological parameters. Moreover, a simple mortality risk level estimation system based on a combination of LOS and age is proposed; the system is simple, highly interpretable, and has strong application value. (C) 2019 Published by Elsevier B.V.
引用
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页数:11
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