The impact of Raman microscopy on the study of artwork and archaeological artefacts is outlined. Important recent case studies are presented to illustrate the power of the technique to answer - either alone or in conjunction with other techniques - key questions of great art historical, conservational, cultural, archaeological and scientific interest. Raman microscopy also offers, via pigment identification, the possibility of testing the attribution of artwork, a matter which should be of great concern to galleries, auction houses and museums.