Flexibility in targeting and insertion during bacterial membrane protein biogenesis

被引：6

作者：

van Bloois, Edwin ^{[1
]}

ten Hagen-Jongman, Corinne M. ^{[1
]}

Luirink, Joen ^{[1
]}

机构：

[1] Vrije Univ Amsterdam, Inst Mol Cell Biol, Dept Mol Microbiol, NL-1081 HV Amsterdam, Netherlands

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2007年 / 362卷 / 03期

关键词：

membrane protein assembly; protein targeting; ribosome; SRP; YidC sec-translocon; Escherichia coli;

D O I：

10.1016/j.bbrc.2007.08.053

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The biogenesis of Escherichia coli inner membrane proteins (IMPs) is assisted by targeting and insertion factors such as the signal recognition particle (SRP), the Sec-translocon and YidC with translocation of (large) periplasmic domains energized by SecA and the proton motive force (pmf). The use of these factors and forces is probably primarily determined by specific structural features of an IMP. To analyze these features we have engineered a set of model IMPs based on endogenous E coli IMPs known to follow distinct targeting and insertion pathways. The modified model IMPs were analyzed for altered routing using an in vivo protease mapping approach. The data suggest a facultative use of different combinations of factors. (c) 2007 Elsevier Inc. All rights reserved.

引用

页码：727 / 733

页数：7

共 50 条

[31] Bacterial outer membrane vesicles in cancer: Biogenesis, pathogenesis, and clinical application [J].

Li, Deming ;

Zhu, Lisi ;

Wang, Yuxiao ;

Zhou, Xiangyu ;

Li, Yan .

BIOMEDICINE & PHARMACOTHERAPY, 2023, 165

[32] Targeting and insertion of heterologous membrane proteins in E-coli [J].

Raine, A ;

Ullers, R ;

Pavlov, M ;

Luirink, J ;

Wikberg, JES ;

Ehrenberg, M .

BIOCHIMIE, 2003, 85 (07) :659-668

[33] Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis [J].

Alvira, Sara ;

Watkins, Daniel W. ;

Troman, Lucy ;

Allen, William J. ;

Lorriman, James S. ;

Degliesposti, Gianluca ;

Cohen, Eli J. ;

Beeby, Morgan ;

Daum, Bertram ;

Gold, Vicki A. M. ;

Skehel, J. Mark ;

Collinson, Ian .

ELIFE, 2020, 9 :1-24

[34] SecA mediates cotranslational targeting and translocation of an inner membrane protein [J].

Wang, Shuai ;

Yang, Chien-I ;

Shan, Shu-ou .

JOURNAL OF CELL BIOLOGY, 2017, 216 (11) :3639-3653

[35] Protein targeting to the ER membrane: multiple pathways and shared machinery [J].

Sanchez, Wendy N. ;

Driessen, Arnold J. M. ;

Wilson, Christian A. M. .

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2025,

[36] Protein targeting to the chloroplast outer membrane [J].

Tu, SL ;

Li, HM .

PHOTOSYNTHESIS: MECHANISMS AND EFFECTS, VOLS I-V, 1998, :3069-3073

[37] Outer membrane protein biogenesis in Gram-negative bacteria [J].

Rollauer, Sarah E. ;

Sooreshjani, Moloud A. ;

Noinaj, Nicholas ;

Buchanan, Susan K. .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2015, 370 (1679)

[38] Protein Transport Across the Bacterial Plasma Membrane by the Sec Pathway [J].

Smets, Dries ;

Loos, Maria S. ;

Karamanou, Spyridoula ;

Economou, Anastassios .

PROTEIN JOURNAL, 2019, 38 (03) :262-273

[39] Protein oligomerization in the bacterial outer membrane [J].

Meng, Guoyu ;

Fronzes, Remi ;

Chandran, Vidya ;

Remaut, Han ;

Waksman, Gabriel .

MOLECULAR MEMBRANE BIOLOGY, 2009, 26 (03) :136-145

[40] Structural Insights into Protein-Protein Interactions Involved in Bacterial Cell Wall Biogenesis [J].

Laddomada, Federica ;

Miyachiro, Mayara M. ;

Dessen, Andrea .

ANTIBIOTICS-BASEL, 2016, 5 (02)

← 1 2 3 4 5 →