Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses

被引：126
作者：
Pavlova, NI
Savinova, OV
Nikolaeva, SN
Boreko, EI
Flekhter, OB
机构：
[1] Belarussian Res Inst Epidemiol & Microbiol, Minsk 220050, BELARUS
[2] Russian Acad Sci, Ufa Res Ctr, Inst Organ Chem, Ufa 450054, Russia
来源：
FITOTERAPIA | 2003年 / 74卷 / 05期
基金：
俄罗斯基础研究基金会;
关键词：
betulin; betulinic acid; betulonic acid; antiviral activity;
D O I：
10.1016/S0367-326X(03)00123-0
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Antiviral properties of betulin, betulinic and betulonic acids were investigated in cell cultures infected with herpes simplex type I, influenza FPV/Rostock and ECHO 6 viruses. All studied tritexpenes were active against herpes simplex virus. Betulin and especially betulinic acid also suppressed ECHO 6 virus reproduction. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：489 / 492
页数：4
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