Seminoma Clinical Stage 1-Patterns of Care in Germany

被引:16
作者
Dieckmann, Klaus-Peter [1 ]
Dralle-Filiz, Inken [1 ]
Heinzelbecker, Julia [4 ]
Matthies, Cord [2 ]
Bedke, Jens [5 ]
Ellinger, Joerg [7 ]
Sommer, Joerg [8 ]
Haben, Bjoern [9 ]
Souchon, Rainer [6 ]
Anheuser, Petra [1 ]
Pichlmeier, Uwe [3 ]
机构
[1] Albertinen Krankenhaus, Urol Klin, Suentelstr 11a, DE-22457 Hamburg, Germany
[2] Bundeswehr Krankenhaus Hamburg, Urol Abt, Hamburg, Germany
[3] Univ Klinikum Eppendorf, Inst Med Stat & Epidemiol, Hamburg, Germany
[4] Univ Klinikum Mannheim, Urol Klin, Mannheim, Germany
[5] Univ Klinikum Tuebingen, Urol Klin, Tubingen, Germany
[6] Univ Klinikum Tuebingen, Klin Radioonkol, Tubingen, Germany
[7] Univ Klinikum Bonn, Urol Klin, Bonn, Germany
[8] St Franziskus Hosp Lohne, Urol Klin, Lohne, Germany
[9] St Marien Krankenhaus Ahaus, Urol Abt, Ahaus, Germany
关键词
Testicular germ cell neoplasms; Seminoma; Patterns of care; Carboplatin; Surveillance; Radiotherapy; I TESTICULAR SEMINOMA; EUROPEAN CONSENSUS CONFERENCE; PRACTICE GUIDELINES; ADJUVANT TREATMENT; CELL-CANCER; SURVEILLANCE; MANAGEMENT; RADIOTHERAPY; TESTIS; DIAGNOSIS;
D O I
10.1159/000443214
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Introduction: International guidelines are ambivalent regarding the recommendations for the management of clinical stage 1 (CS1) seminoma. Patients and Methods: During 2008-2013, 1,050 patients with seminoma CS1 were prospectively registered with regard to assessing management modality (radiotherapy, carboplatin, surveillance). Associations with tumor size, rete testis invasion, age, year of diagnosis, type of institution, and geographic location were assessed. Results: Of the total number of patients, 49.3% received carboplatin 1 course, 8.5% carboplatin 2 courses, 35.9% surveillance, and 6.3% radiotherapy. In 2013, surveillance increased significantly to 57.9%. Treatment decisions were significantly associated with rete testis invasion and tumor size. Carboplatin was applied significantly more in office clinics than elsewhere. There is some regional variation regarding treatment preferences. Conclusions: The rising acceptance of surveillance mirrors international trends. The associations with prognostic factors demonstrate care givers to be compliant with contemporary guidelines. The association with the type of institution suggests non-oncological factors to be also relevant in decision making. (C) 2016 S. Karger AG, Basel
引用
收藏
页码:390 / 398
页数:9
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