Applicable Life-History and Molecular Traits for Studying the Effects of Anhydrobiosis on Aging in Tardigrades

被引:5
作者
Nagwani, Amit Kumar [1 ]
Kaczmarek, Lukasz [2 ]
Kmita, Hanna [1 ,3 ]
机构
[1] Adam Mickiewicz Univ Pozna, Fac Biol, Dept Bioenerget, Uniwersytetu Poznanskiego 6, PL-61614 Poznan, Poland
[2] Adam Mickiewicz Univ, Fac Biol, Dept Anim Taxon & Ecol, Uniwersytetu Poznanskiego 6, PL-61614 Poznan, Poland
[3] Adam Mickiewicz Univ, Fac Biol, Inst Mol Biol & Biotechnol, Dept Bioenerget, Uniwersytetu Poznanskiego 6, PL-61614 Poznan, Poland
来源
DIVERSITY-BASEL | 2022年 / 14卷 / 08期
关键词
tardigrades; anhydrobiosis; aging; Sleeping Beauty; The Picture of Dorian Gray; life-history traits; cellular traits; SPONTANEOUS LOCOMOTOR-ACTIVITY; OXIDATIVE STRESS; RECOMMENDED ABBREVIATIONS; ANTIOXIDANT DEFENSES; CELLULAR-RESPONSES; MITOCHONDRIAL-DNA; MODEL ORGANISM; TUN FORMATION; LIVING THEORY; DESICCATION;
D O I
10.3390/d14080664
中图分类号
X176 [生物多样性保护];
学科分类号
090705 ;
摘要
Anhydrobiosis is induced by loss of water and indicates dehydration tolerance. Survival of dehydration is possible through changes at different levels of organism organization, including a remarkable reduction in metabolic activity at the cellular level. Thus, anhydrobiosis may be regarded as an anti-aging strategy. Accordingly, two hypotheses named after popular stories, "Sleeping Beauty" and "The Picture of Dorian Gray", were proposed to explain the effect of anhydrobiosis on aging. The two hypotheses predict the presence (The Picture of Dorian Gray) or absence (Sleeping Beauty) of observable aging symptoms for animals undergoing anhydrobiosis. Predictions of these hypotheses have rarely been tested, and the cellular level has not been addressed. Tardigrades appear to be a useful model for studying the effect of anhydrobiosis on aging, as they are able to enter and survive anhydrobiosis at any stage of life, although not with the same success for all species. In this review, we discuss anhydrobiosis and aging mechanisms as well as tardigrade diversity and indicate possible multilevel markers that can be used to study the impact of anhydrobiosis on tardigrade aging. This review provides data on tardigrade diversity that may also be useful for human aging studies.
引用
收藏
页数:19
相关论文
共 183 条
[1]   In Response to Abiotic Stress, DNA Methylation Confers EpiGenetic Changes in Plants [J].
Akhter, Zahida ;
Bi, Zhenzhen ;
Ali, Kazim ;
Sun, Chao ;
Fiaz, Sajid ;
Haider, Fasih Ullah ;
Bai, Jiangping .
PLANTS-BASEL, 2021, 10 (06)
[2]   Phenotypic variations in the life history of two clones of Macrobiotus richtersi (Eutardigrada, Macrobiotidae) [J].
Altiero, T ;
Rebecchi, L ;
Bertolani, R .
HYDROBIOLOGIA, 2006, 558 (1) :33-40
[3]   Rearing tardigrades: Results and problems [J].
Altiero, T ;
Rebecchi, L .
ZOOLOGISCHER ANZEIGER, 2001, 240 (3-4) :217-221
[4]   Life history traits and reproductive mode of the tardigrade Acutuncus antarcticus under laboratory conditions: strategies to colonize the Antarctic environment [J].
Altiero, Tiziana ;
Giovannini, Ilaria ;
Guidetti, Roberto ;
Rebecchi, Lorena .
HYDROBIOLOGIA, 2015, 761 (01) :277-291
[5]   Mitochondrial and metabolic dysfunction in ageing and age-related diseases [J].
Amorim, Joao A. ;
Coppotelli, Giuseppe ;
Rolo, Anabela P. ;
Palmeira, Carlos M. ;
Ross, Jaime M. ;
Sinclair, David A. .
NATURE REVIEWS ENDOCRINOLOGY, 2022, 18 (04) :243-258
[6]   METABOLIC RATES IN GENETICALLY BASED LONG LIVED STRAINS OF DROSOPHILA [J].
ARKING, R ;
BUCK, S ;
WELLS, RA ;
PRETZLAFF, R .
EXPERIMENTAL GERONTOLOGY, 1988, 23 (01) :59-76
[7]   Diverse aging rates in metazoans: targets for functional genomics [J].
Austad, SN .
MECHANISMS OF AGEING AND DEVELOPMENT, 2005, 126 (01) :43-49
[8]   Role of Mitochondria in Radiation Responses: Epigenetic, Metabolic, and Signaling Impacts [J].
Averbeck, Dietrich ;
Rodriguez-Lafrasse, Claire .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (20)
[9]  
BAKER GT, 1988, EXP GERONTOL, V23, P223, DOI 10.1016/0531-5565(88)90025-3
[10]   The flux of free radical attack through mitochondrial DNA is related to aging rate [J].
Barja, G .
AGING CLINICAL AND EXPERIMENTAL RESEARCH, 2000, 12 (05) :342-355