Medicinal applications of metal-peptide bioconjugates

被引:64
作者
Metzler-Nolte, Nils [1 ]
机构
[1] Ruhr Univ Bochum, Dept Chem & Biochem, Lehrstuhl Anorgan Chem 1, D-44801 Bochum, Germany
关键词
bioconjugates; bioorganometallic chemistry; ferrocene; peptides; solid-phase synthesis;
D O I
10.2533/chimia.2007.736
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Organometal-peptide bioconjugates have a variety of applications in biomedical studies, such as antiproliferative and anti-bacterial activity, as well as to aid the elucidation of the mode of action of the conjugated metal complexes. Our group has developed the solid-phase synthesis of organometal-peptides by different synthesis schemes, their characterization and use in biomedical studies. Selected examples are presented in this review.
引用
收藏
页码:736 / 741
页数:6
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