Medicinal applications of metal-peptide bioconjugates

被引：64
|
作者：
Metzler-Nolte, Nils [1 ]
机构：
[1] Ruhr Univ Bochum, Dept Chem & Biochem, Lehrstuhl Anorgan Chem 1, D-44801 Bochum, Germany
来源：
CHIMIA | 2007年 / 61卷 / 11期
关键词：
bioconjugates; bioorganometallic chemistry; ferrocene; peptides; solid-phase synthesis;
D O I：
10.2533/chimia.2007.736
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Organometal-peptide bioconjugates have a variety of applications in biomedical studies, such as antiproliferative and anti-bacterial activity, as well as to aid the elucidation of the mode of action of the conjugated metal complexes. Our group has developed the solid-phase synthesis of organometal-peptides by different synthesis schemes, their characterization and use in biomedical studies. Selected examples are presented in this review.
引用
收藏
页码：736 / 741
页数：6
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