Medicinal applications of metal-peptide bioconjugates

被引：64

作者：

Metzler-Nolte, Nils ^{[1
]}

机构：

[1] Ruhr Univ Bochum, Dept Chem & Biochem, Lehrstuhl Anorgan Chem 1, D-44801 Bochum, Germany

来源：

CHIMIA | 2007年 / 61卷 / 11期

关键词：

bioconjugates; bioorganometallic chemistry; ferrocene; peptides; solid-phase synthesis;

D O I：

10.2533/chimia.2007.736

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Organometal-peptide bioconjugates have a variety of applications in biomedical studies, such as antiproliferative and anti-bacterial activity, as well as to aid the elucidation of the mode of action of the conjugated metal complexes. Our group has developed the solid-phase synthesis of organometal-peptides by different synthesis schemes, their characterization and use in biomedical studies. Selected examples are presented in this review.

引用

页码：736 / 741

页数：6

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