Longitudinal Relationship Between Frailty and Cognitive Impairment in Chinese Older Adults: A Prospective Study

被引：10

作者：

Zhao, Xinxin ^{[1
,2
]}

Chen, Qi ^{[3
]}

Zheng, Liang ^{[4
]}

Ren, Longbing ^{[2
]}

Zhai, Yinghong ^{[2
]}

Li, Jue ^{[1
,2
]}

He, Jia ^{[2
]}

机构：

[1] Tongji Univ, Clin Res Ctr Mental Disorders, Shanghai Pudong New Area Mental Hlth Ctr, Sch Med, 165 Sanlin Rd, Shanghai 200124, Peoples R China

[2] Tongji Univ, Sch Med, 1239 Siping Rd, Shanghai 200092, Peoples R China

[3] Navy Med Univ, Dept Hlth Stat, Shanghai, Peoples R China

[4] Tongji Univ, Shanghai East Hosp, Res Ctr Translat Med, Sch Med, Shanghai, Peoples R China

来源：

JOURNAL OF APPLIED GERONTOLOGY | 2022年 / 41卷 / 12期

基金：

国家重点研发计划;

关键词：

frailty; cognitive function; older adults; cohort study; activities of daily living; MORTALITY; PEOPLE; ASSOCIATION; DEMENTIA; DISEASE; POLICY; INDEX;

D O I：

10.1177/07334648221118352

中图分类号：

R4 [临床医学]; R592 [老年病学];

学科分类号：

1002 ; 100203 ; 100602 ;

摘要：

We aimed to examine the longitudinal association between frailty and cognitive impairment in the older Chinese population. This prospective cohort study used data from the Chinese Longitudinal Healthy Longevity Study 2011 wave. We calculated the follow-up duration as 3 years from the baseline year. Frailty was measured using the frailty index, and cognitive function was calculated by Mini-Mental State Examination Scale. Participants who were non-frailty and those with normal cognitive function were included in 2011 and followed up in 2014, respectively. Frailty was an independent risk factor for early-onset cognitive impairment. Age, hearing impairment, and a decreased ability to perform daily activities were the main risk factors for cognitive impairment, while affluent economic status was a protective factor. Cognitive impairment was not found to be an independent risk factor for frailty. We concluded that the frailty index is a significant predictor of cognitive impairment among community-dwelling older adults.

引用

页码：2490 / 2498

页数：9

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