MR imaging probes: design and applications

被引：121

作者：

Boros, Eszter

Gale, Eric M.

Caravan, Peter ^{[1
]}

机构：

[1] Massachusetts Gen Hosp, Dept Radiol, Athinoula A Martinos Ctr Biomed Imaging, Charlestown, MA 02129 USA

来源：

DALTON TRANSACTIONS | 2015年 / 44卷 / 11期

基金：

瑞士国家科学基金会;

关键词：

HUMAN SERUM-ALBUMIN; AORTOILIAC OCCLUSIVE DISEASE; ANGIOGRAPHY CONTRAST AGENT; SATURATION-TRANSFER CEST; WATER EXCHANGE-RATE; HIGH-RELAXIVITY; PROTEIN-BINDING; GADOLINIUM COMPLEX; GD3+ COMPLEXES; ENHANCED MRI;

D O I：

10.1039/c4dt02958e

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

This perspective outlines strategies towards the development of MR imaging probes that our lab has explored over the last 15 years. Namely, we discuss methods to enhance the signal generating capacity of MR probes and how to achieve tissue specificity through protein targeting or probe activation within the tissue microenvironment.

引用

收藏

页码：4804 / 4818

页数：15

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