Canine lymphosarcoma: Diagnosis and treatment

This article discusses the diagnostic and treatment approach to canine lymphosarcoma (LSA), Several conclusions can be drawn from the extensive body of studies on canine LSA in clinical and pathologic medicine: It is now recognized that this disease has great clinical and histologic heterogeneity; in most cases, survival can be improved with combination chemotherapy; and drug resistance is a major impediment to treating the relapsed disease. Different chemotherapy regimens are discussed along with their survival rates. Newer drugs undergoing clinical trials and the mechanism of drug resistance eventually leading to therapy failure are also discussed. Most clients are very satisfied with chemotherapy for their pets because It provides prolonged, good-quality survival and the side effects are reasonably mild.