AN EFFICIENT SYNTHESIS OF 2-AMINOBENZOXAZOLES AND 2-AMINOBENZOTHIAZOLES FROM 2-AMINOPHENOLS OR 2-AMINOTHIOPHENOLS AND ISOSELENOCYANATES

被引：7

作者：

Xie, Yuanyuan ^{[1
]}

Zhang, Fan ^{[1
]}

Chen, Xiaodong ^{[1
]}

Li, Jianjun ^{[1
]}

机构：

[1] Zhejiang Univ Technol, Key Lab Pharmaceut Engn, Minist Educ, Coll Pharmaceut Sci, Hangzhou 310014, Zhejiang, Peoples R China

来源：

HETEROCYCLES | 2010年 / 81卷 / 09期

基金：

中国国家自然科学基金;

关键词：

Isoselenocyanate; 2-Aminobenzoxazole; 2-Aminobenzothiazole; Deselenizing Reaction; Synthesis; SELENIUM-CONTAINING HETEROCYCLES; 2-SUBSTITUTED AMINOBENZOXAZOLES; DERIVATIVES; N-(2-HYDROXYPHENYL)-N'-PHENYLTHIOUREAS; BENZOTHIAZOLE; SELENOUREAS; SUPEROXIDE; ANTAGONIST; ACID;

D O I：

10.3987/COM-10-11987

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An expeditious method to access 2-aminobenzoxazoles and 2-aminobenzothiazoles from various substituted 2-aminophenols and 2-aminothiophenols, respectively, with isoselenocyanates in a one pot procedure is reported. Elemental Se precipitates nearly quantitatively in the reaction without any deselenizing agent and it can be reused. A possible mechanism for the formation of the target products is proposed.

引用

页码：2087 / 2096

页数：10

共 45 条

[1]

[Anonymous], 1999, ORGANOSELENIUM CHEM

[2]

BRITTAIN DR, 2000, Patent No. 200005223

[3] THE NEAR-ULTRA-VIOLET ABSORPTION SPECTRA OF SOME HETEROCYCLIC COMPOUNDS .2. BENZOTHIAZOLES [J].