Computational Study of Intramolecular Arene Palladation at a Palladium(IV) Center

被引:21
作者
Canty, Allan J. [1 ]
Ariafard, Alireza [1 ]
Yates, Brian F. [1 ]
Sanford, Melanie S. [2 ]
机构
[1] Univ Tasmania, Sch Phys Sci, Hobart, Tas 7001, Australia
[2] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
基金
澳大利亚研究理事会;
关键词
H BOND ACTIVATION; METALATION-DEPROTONATION MECHANISM; PROTON-ABSTRACTION MECHANISM; CATALYZED DIRECT ARYLATION; COUPLING REACTIONS; SITE-SELECTIVITY; ANCILLARY-LIGAND; FUNCTIONALIZATION; REGIOSELECTIVITY; REACTIVITY;
D O I
10.1021/om5013049
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A computational study of the palladation of a pendant phenyl group in the Pd-IV complex PdCl2(CF3)(biH)(Bu(2)(t)bpy) to form PdCl(CF3)(bi)(Bu(2)(t)bpy) (bi = biphenylenediyl) indicates that this reaction occurs via an SEAr mechanism after dissociation of a chloride ion from the Pd center. Chloride dissociation occurs trans to the Pd-C(biH) bond. This dissociation is followed by rate-limiting isomerization of the square-pyramidal five-coordinate cation to place the remaining chloride ligand trans to the pendant phenyl group, with concomitant formation of a Pd-arenonium species. The free chloride ion then assists the departure of the Cipso proton from the arenonium complex as HCl. Key findings of this study include the occurrence of facile ligand dissociation and isomerization at this PdIVcenter as well as the participation of a classical SEAr mechanistic pathway in this transformation.
引用
收藏
页码:1085 / 1090
页数:6
相关论文
共 69 条
[1]   Carboxylate-Assisted Transition-Metal-Catalyzed C-H Bond Functionalizations: Mechanism and Scope [J].
Ackermann, Lutz .
CHEMICAL REVIEWS, 2011, 111 (03) :1315-1345
[2]   Regioselective ortho palladation of stabilized iminophosphoranes in exo positions:: Scope, limitations, and mechanistic insights [J].
Aguilar, David ;
Bielsa, Raquel ;
Contel, Maria ;
Lledos, Agusti ;
Navarro, Rafael ;
Soler, Tatiana ;
Urriolabeitia, Esteban P. .
ORGANOMETALLICS, 2008, 27 (13) :2929-2936
[3]   Non-innocent Additives in a Palladium(II)-Catalyzed C-H Bond Activation Reaction: Insights into Multimetallic Active Catalysts [J].
Anand, Megha ;
Sunoj, Raghavan B. ;
Schaefer, Henry F., III .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 136 (15) :5535-5538
[4]   ENERGY-ADJUSTED ABINITIO PSEUDOPOTENTIALS FOR THE 2ND AND 3RD ROW TRANSITION-ELEMENTS [J].
ANDRAE, D ;
HAUSSERMANN, U ;
DOLG, M ;
STOLL, H ;
PREUSS, H .
THEORETICA CHIMICA ACTA, 1990, 77 (02) :123-141
[5]  
[Anonymous], J PHYS CHEM A
[6]   Cyclometallation of amino-imines on palladium complexes. The effect of the solvent on the experimental and calculated mechanism [J].
Aullon, Gabriel ;
Chat, Romain ;
Favier, Isabelle ;
Font-Bardia, Merce ;
Gomez, Montserrat ;
Granell, Jaume ;
Martinez, Manuel ;
Solans, Xavier .
DALTON TRANSACTIONS, 2009, (39) :8292-8300
[7]   C-H Bond Activation in Transition Metal Species from a Computational Perspective [J].
Balcells, David ;
Clot, Eric ;
Eisenstein, Odile .
CHEMICAL REVIEWS, 2010, 110 (02) :749-823
[8]   Selective cyclopalladation of R3P=NCH2Aryl iminophosphoranes, experimental and computational study [J].
Bielsa, Raquel ;
Navarro, Rafael ;
Urriolabeitia, Esteban P. ;
Lledos, Agusti .
INORGANIC CHEMISTRY, 2007, 46 (24) :10133-10142
[9]   C-H bond activation of benzene and methane by M(η2-O2CH)2 (M = Pd or Pt).: A theoretical study [J].
Biswas, B ;
Sugimoto, M ;
Sakaki, S .
ORGANOMETALLICS, 2000, 19 (19) :3895-3908
[10]   VAN DER WAALS VOLUMES + RADII [J].
BONDI, A .
JOURNAL OF PHYSICAL CHEMISTRY, 1964, 68 (03) :441-+