Early signs, diagnosis and therapeutics of the prodromal phase of schizophrenia and related psychotic disorders

被引:79
作者
Larson, Molly K. [2 ]
Walker, Elaine F. [2 ]
Compton, Michael T. [1 ]
机构
[1] Emory Univ, Sch Med, Dept Psychiat & Behav Sci, Atlanta, GA 30322 USA
[2] Emory Univ, Dept Psychol, Grad Sch Arts & Sci, Atlanta, GA 30322 USA
关键词
cognitive-behavioral therapy; early intervention; olanzapine; omega-3 fatty acids; prodrome; psychosis; risperidone; ultra-high risk; ziprasidone; ULTRA-HIGH-RISK; RANDOMIZED CONTROLLED-TRIAL; ETHYL-EICOSAPENTAENOIC ACID; COGNITIVE-BEHAVIOR THERAPY; PLACEBO-CONTROLLED-TRIAL; 1ST-EPISODE PSYCHOSIS; UNTREATED PSYCHOSIS; FOLLOW-UP; NEUROCOGNITIVE DEFICITS; SPECTRUM DISORDERS;
D O I
10.1586/ERN.10.93
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
During recent decades, interest in the prevention of mental illnesses has increased. Improved diagnostic tools, the advent of atypical antipsychotic medications and the development of phase-specific psychosocial treatments have made intervention research in people at ultra-high risk for developing schizophrenia or a related psychotic disorder possible. Preliminary data suggest that low doses of atypical antipsychotic medications augmented by psychosocial treatments may delay the onset of psychosis in some individuals. Findings support further research for the establishment of best-practice standards.
引用
收藏
页码:1347 / 1359
页数:13
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