Bis{(E)-N′-[2,4-bis(trifluoromethyl)benzylidene]isonicotinohydrazide} monohydrate

被引：3

作者：

Naveenkumar, H. S. ^{[2
]}

Sadikun, Amirin ^{[2
]}

Ibrahim, Pazilah ^{[2
]}

Yeap, Chin Sing ^{[1
]}

Fun, Hoong-Kun ^{[1
]}

机构：

[1] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, Usm 11800, Penang, Malaysia

[2] Univ Sains Malaysia, Sch Pharmaceut Sci, Usm 11800, Penang, Malaysia

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2010年 / 66卷

关键词：

D O I：

10.1107/S1600536810025493

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The asymmetric unit of the title compound, 2C(15)H(9)F(6)N(3)O center dot H2O, contains two independent Schiff base molecules and one water molecule. Both Schiff base molecules exist in an E configuration with respect to the C=N double bonds and the dihedral angles between the benzene and the pyridine rings in the two molecules are 17.53 (12) and 20.62 (12)degrees. In the crystal structure, molecules are linked by intermolecular N-H...O and C-H...O hydrogen bonds into infinite one-dimensional chains along the a axis. In addition, intermolecular O-H...N, O-H...F, C-H...F and C-H...O hydrogen bonds further link these chains into a three-dimensional network. Weak pi-pi interactions with centroid-centroid distances in the range 3.6495 (17)-3.7092 (16) A are also observed.

引用

页码：O1918 / U346

页数：14

共 12 条

[1]

[Anonymous], 2009, APEX2 SAINT SADABS

[2] A NITROGEN-GAS-STREAM CRYOSTAT FOR GENERAL X-RAY-DIFFRACTION STUDIES [J].

COSIER, J ;

GLAZER, AM .

JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1986, 19 (02) :105-107

[3] Synthesis and anti-mycobacterial activity of (E)-N′-(monosubstituted-benzylidene)isonicotinohydrazide derivatives [J].

da Silva Lourenco, Maria Cristina ;

Ferreira, Marcelle de Lima ;

Nora de Souza, Marcus Vinicius ;

Peralta, Monica Amado ;

Alves Vasconcelos, Thatyana Rocha ;

Henriques, Maria das Gracas M. O. .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 43 (06) :1344-1347

[4] Antituberculosis drugs: Ten years of research [J].

Janin, Yves L. .

BIOORGANIC & MEDICINAL CHEMISTRY, 2007, 15 (07) :2479-2513

[5] SYNTHESIS OF HOMODINUCLEAR MACROCYCLIC COMPLEXES OF LANTHANIDES AND PHENOLIC SCHIFF-BASES [J].

KAHWA, IA ;

SELBIN, J ;

HSIEH, TCY ;

LAINE, RA .

INORGANICA CHIMICA ACTA, 1986, 118 (02) :179-185

[6] In vitro advanced antimycobacterial screening of isoniazid-related hydrazones, hydrazides and cyanoboranes:: Part 14 [J].

Maccari, R ;

Ottanà, R ;

Vigorita, MG .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (10) :2509-2513

[7] (E)-N′-(2,4,5-Trimethoxybenzylidene)isonicotinohydrazide dihydrate [J].

Naveenkumar, H. S. ;

Sadikun, Amirin ;

Ibrahim, Pazilah ;

Yeap, Chin Sing ;

Fun, Hoong-Kun .

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 :O1235-U1401

[8] (E)-N′-(2,4,5-Trifluorobenzylidene)isonicotinohydrazide monohydrate [J].

Naveenkumar, H. S. ;

Sadikun, Amirin ;

Ibrahim, Pazilah ;

Yeap, Chin Sing ;

Fun, Hoong-Kun .

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 :O579-U4704

[9] (E)-N′-(3-Benzyloxy-4-methoxybenzylidene)isonicotinohydrazide [J].

Naveenkumar, H. S. ;

Sadikun, Amirin ;

Ibrahim, Pazilah ;

Loh, Wan-Sin ;

Fun, Hoong-Kun .

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 :O2540-+

[10] A short history of SHELX [J].

Sheldrick, George M. .

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2008, 64 :112-122

← 1 2 →