N-terminal fragments of mutant huntingtin form filamentous aggregates in HD brain

被引：0
|
作者：
Yi, H [1 ]
Li, SH [1 ]
Li, XJ [1 ]
Hersch, SM [1 ]
Gutekunst, CA [1 ]
机构：
[1] Emory Univ, Sch Med, Dept Neurol, Atlanta, GA 30322 USA
来源：
ELECTRON MICROSCOPY 1998, VOL 1: GENERAL INTEREST AND INSTRUMENTATION | 1998年
关键词：
D O I：
暂无
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
引用
收藏
页码：843 / 844
页数：2
相关论文
共 50 条
  • [21] A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin
    Damiano, Maria
    Diguet, Elsa
    Malgorn, Carole
    D'Aurelio, Marilena
    Galvan, Laurie
    Petit, Fanny
    Benhaim, Lucile
    Guillermier, Martine
    Houitte, Diane
    Dufour, Noelle
    Hantraye, Philippe
    Canals, Josep M.
    Alberch, Jordi
    Delzescaux, Thierry
    Deglon, Nicole
    Beal, M. Flint
    Brouillet, Emmanuel
    HUMAN MOLECULAR GENETICS, 2013, 22 (19) : 3869 - 3882
  • [22] Modulation of Mutant Huntingtin N-Terminal Cleavage and Its Effect on Aggregation and Cell Death
    Katrin Juenemann
    Christina Weisse
    Denise Reichmann
    Christoph Kaether
    Cornelis F. Calkhoven
    Gabriele Schilling
    Neurotoxicity Research, 2011, 20 : 120 - 133
  • [23] Promoters Are Differentially Sensitive to N-Terminal Mutant Huntingtin-Mediated Transcriptional Repression
    Hogel, Matthew
    Laprairie, Robert B.
    Denovan-Wright, Eileen M.
    PLOS ONE, 2012, 7 (07):
  • [24] Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation
    Havel, Lauren S.
    Wang, Chuan-En
    Wade, Brandy
    Huang, Brenda
    Li, Shihua
    Li, Xiao-Jiang
    HUMAN MOLECULAR GENETICS, 2011, 20 (07) : 1424 - 1437
  • [25] Modulation of Mutant Huntingtin N-Terminal Cleavage and Its Effect on Aggregation and Cell Death
    Juenemann, Katrin
    Weisse, Christina
    Reichmann, Denise
    Kaether, Christoph
    Calkhoven, Cornelis F.
    Schilling, Gabriele
    NEUROTOXICITY RESEARCH, 2011, 20 (02) : 120 - 133
  • [26] Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin (vol 8, pg 397, 1999)
    Schilling, G
    Becher, MW
    Sharp, AH
    Jinnah, HA
    Duan, K
    Kotzuk, JA
    Slunt, HH
    Ratovitski, T
    Cooper, JK
    Jenkins, NA
    Copeland, NG
    Price, DL
    Ross, CA
    Borchelt, DR
    HUMAN MOLECULAR GENETICS, 1999, 8 (05) : 943 - 943
  • [27] Expanded Polyglutamine-containing N-terminal Huntingtin Fragments Are Entirely Degraded by Mammalian Proteasomes
    Juenemann, Katrin
    Schipper-Krom, Sabine
    Wiemhoefer, Anne
    Kloss, Alexander
    Sanz, Alicia Sanz
    Reits, Eric A. J.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (38) : 27068 - 27084
  • [28] Effect of post-mortem delay on N-terminal huntingtin protein fragments in human control and Huntington disease brain lysates
    Schut, Menno H.
    Patassini, Stefano
    Kim, Eric H.
    Bullock, Jocelyn
    Waldvogel, Henry J.
    Faull, Richard L. M.
    Pepers, Barry A.
    den Dunnen, Johan T.
    van Ommen, Gert-Jan B.
    van Roon-Mom, Willeke M. C.
    PLOS ONE, 2017, 12 (06):
  • [29] MUTANT HUNTINGTIN AGGREGATES IN HUMAN HD ARE FOCUSED TO EMOTION-RELATED CORTICES
    Scheunemann, Paul G.
    von Hein, Sarah M.
    Bader, Verian
    Parwez, Constanze R.
    Winklhofer, Konstanze F.
    Foester, Eckart
    Saft, Carsten
    Petrasch-Parwez, Elisabeth
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2022, 93 : A6 - A6
  • [30] Regulation of Mutant Huntingtin Mitochondrial Toxicity by Phosphomimetic Mutations within Its N-Terminal Region
    Yablonska, Svitlana
    Strohlein, Colleen E.
    Baranov, Sergei V.
    Yeh, Stacy M.
    Patel, Aashka
    Singh, Tanisha
    Jauhari, Abhishek
    Kim, Jinho
    Khattar, Nicolas K.
    Li, Fang
    Wang, Xiaomin
    Chang, Yue-Fang
    Lee, C. Y. Daniel
    Yang, X. William
    Carlisle, Diane L.
    Friedlander, Robert M.
    JOURNAL OF NEUROSCIENCE, 2025, 45 (08):
12345