Clinically misinterpreted melanoma metastases can correctly be diagnosed by ultrasound-guided fine needle aspiration cytology

被引:4
作者
Schaefer-Hesterberg, Gregor [1 ]
Van Akkooi, Alexander J. C. [2 ]
Letsch, Anne [3 ]
Roewert, Joachim [1 ]
Blume-Peytavi, Ulrike [1 ]
Keilholz, Ulrich [3 ]
Voit, Christiane [1 ]
机构
[1] Charite, Dept Dermatol Venerol & Allergol, D-10117 Berlin, Germany
[2] Erasmus Univ, Med Ctr, Daniel den Hoed Canc Ctr, Dept Surg Oncol, NL-3000 DR Rotterdam, Netherlands
[3] Charite, Dept Hematol & Med Oncol, D-10117 Berlin, Germany
关键词
FNAC; lipoma; melanoma; metastases; ultrasound; NODE;
D O I
10.1684/ejd.2011.1275
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Ultrasound-guided fine needle aspiration cytology (US-guided FNAC) of regional nodal basins is increasingly incorporated into the national follow-up schemes of high risk melanoma patients. In this paper we describe an additional added value of US-guided FNAC in the detection and verification of subcutaneous/in-transit metastases. A patient presented with a long lasting, smooth, movable node, close to the scar of the primary melanoma, mimicking a lipoma in every clinical follow-up. Ultrasound at once suspected a metastasis. FNAC was performed within one day of sampling in an outpatient setting, without side effects. A hypothesis of an auto-vaccination in this case could not be proven by examining the T-cell response. Despite the clinically benign aspect of this metastasis, US-guided FNAC can provide diagnosis within 1 day. FNAC is a rapid, cost-effective method, free of complications, of great value in the diagnosis of putative metastases.
引用
收藏
页码:238 / 241
页数:4
相关论文
共 9 条
[1]   Ultrasonographic and power Doppler appearance of locoregional metastases from cutaneous melanoma [J].
Calvo Lopez, M. J. ;
Vallejos Roca, E. ;
Munoz Alcantara, I. ;
Navarro Diaz, F. ;
Garcia Palacios, M. V. .
RADIOLOGIA, 2008, 50 (06) :483-488
[2]  
Garbe Claus, 2006, J Dtsch Dermatol Ges, V4, P344, DOI 10.1111/j.1610-0387.2006.05891.x
[3]   Use of ultrasound to early identify diagnose and localize metastases in melanoma patients [J].
Schaefer-Hesterberg, Gregor ;
Schoengen, Alfred ;
Sterry, Wolfram ;
Voit, Christiane .
EXPERT REVIEW OF ANTICANCER THERAPY, 2007, 7 (12) :1707-1716
[4]   Long-term freedom from recurrence in 2 stage IV melanoma patients following vaccination with tyrosinase peptides [J].
Scheibenbogen, C ;
Nagorsen, D ;
Seliger, B ;
Schmittel, A ;
Letsch, A ;
Bauer, S ;
Max, N ;
Bock, M ;
Atkins, D ;
Thiel, EH ;
Keilholz, U .
INTERNATIONAL JOURNAL OF CANCER, 2002, 99 (03) :403-408
[5]  
Voit C, 2000, CANCER CYTOPATHOL, V90, P186, DOI 10.1002/1097-0142(20000625)90:3<186::AID-CNCR7>3.3.CO
[6]  
2-F
[7]   Ultrasound-guided fine needle aspiration cytology prior to sentinel lymph node biopsy in melanoma patients [J].
Voit, Christiane ;
Kron, Martina ;
Schaefer, Gregor ;
Schoengen, Alfred ;
Audring, Heike ;
Lukowsky, Ansgar ;
Schwuerzer-Voit, Markus ;
Sterry, Wolfram ;
Winter, Helmut ;
Rademaker, Juergen .
ANNALS OF SURGICAL ONCOLOGY, 2006, 13 (12) :1682-1689
[8]   Impact of Molecular Staging Methods in Primary Melanoma: Reverse-Transcriptase Polymerase Chain Reaction (RT-PCR) of Ultrasound-Guided Aspirate of the Sentinel Node Does Not Improve Diagnostic Accuracy, But RT-PCR of Peripheral Blood Does Predict Survival [J].
Voit, Christiane A. ;
Schaefer-Hesterberg, Gregor ;
Kron, Martina ;
van Akkooi, Alexander C. J. ;
Rademaker, Juergen ;
Lukowsky, Ansgar ;
Schoengen, Alfred ;
Schwuerzer-Voit, Markus ;
Sterry, Wolfram ;
Krause, Markus ;
Roewert-Huber, Joachim ;
Eggermont, Alexander M. M. .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (35) :5742-5747
[9]  
Volt C, 2001, CANCER, V91, P2409