4-Deacetylbaccatin III: a Proposed Biosynthetic Precursor of Paclitaxel from the Bark of Taxus wallichiana

被引：0

作者：

Nisar, Muhammad ^{[1
]}

Qayum, Mughal ^{[2
]}

Adhikari, Achyut ^{[3
]}

Khan, Inamullah ^{[2
]}

Kaleem, Waqar Ahamad ^{[2
]}

Ali, Zulfiqar ^{[3
]}

Choudhary, M. Iqbal ^{[3
]}

机构：

[1] Univ Peshawar, Inst Chem Sci, Peshawar 25120, Nwfp, Pakistan

[2] Univ Peshawar, Dept Pharm, Peshawar 25120, Pakistan

[3] Univ Karachi, H E J Res Inst Chem, Int Ctr Chem & Biol Sci, Karachi 75270, Pakistan

来源：

NATURAL PRODUCT COMMUNICATIONS | 2010年 / 5卷 / 11期

关键词：

Taxus wallichiana; Taxaceae; 4-deacetylbaccatin III; ZUCC;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

4-Deacetylbaccatin III was Isolated and characterized from the bark of Taxus wallichiana Zucc It was previously identified as an intermediate during the synthesis of paclitaxel and was proposed as a precursor for the biosynthesis of paclitaxel Existence of 4-deacetylbaccatin III in T wallichiana is strong evidence for the previously proposed biosynthetic pathway of paclitaxel via 4-deacetylbaccatin III

引用

页码：1727 / 1728

页数：2

共 6 条

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