A Novel and One-Pot Multicomponent Approach to the Synthesis of Dihyroindeno[1,2-b]pyrroles and Indeno[2′,1′:4,5]pyrrolo[1,2-a]-Fused 1,3-Diazaheterocycles

被引：23
作者：
Alizadeh, Abdolali [1 ]
Zarei, Ameneh [1 ]
Rezvanian, Atieh [1 ]
机构：
[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran
来源：
SYNTHESIS-STUTTGART | 2011年 / 03期
关键词：
1,1-bis(methylthio)-2-nitroethene; ninhydrin; indeno[1,2-b]pyrrole; multicomponent reaction; HETEROCYCLIC KETENE AMINALS; LACTAM-FUSED DIAZAHETEROCYCLES; HIGHLY SUBSTITUTED PYRROLES; GRAM-POSITIVE BACTERIA; AZA-ENE REACTION; 4-COMPONENT REACTION; CYCLOCONDENSATION REACTIONS; TETRASUBSTITUTED PYRROLES; CARBONYL-COMPOUNDS; ETHYL PROPIOLATE;
D O I：
10.1055/s-0030-1258383
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An easy, highly efficient, and simple one-pot approach for the synthesis of dihyroindeno[1,2-b]pyrroles and indeno[2',1':4,5]pyrrolo[1,2-a]-fused 1,3-diazaheterocycles under mild conditions is reported. The reaction of a primary amine or 1,n-diamine with 1,1-bis(methylthio)-2-nitroethene in the presence of ninhydrin in aqueous media afforded the title compounds in good yields.
引用
收藏
页码：497 / 501
页数：5
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