Titanium scaffolds for osteointegration: mechanical, in vitro and corrosion behaviour

被引:83
作者
Cachinho, Sandra C. P. [1 ]
Correia, Rui N. [1 ]
机构
[1] Univ Aveiro, Dept Ceram & Glass Engn, P-3810193 Aveiro, Portugal
关键词
D O I
10.1007/s10856-006-0052-7
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
While titanium has been successful as an orthopaedic or dental implant material, performance problems still persist concerning implant-bone interfacial strength and mechanical modulus mismatch between metal and tissue. Porous structures are an advantageous alternative because the elastic modulus can be adjusted to match that of bone, thereby preventing bone resorption. Furthermore, to achieve early and strong stabilization theses structures may be coated with bioactive deposits, as hydroxyapatite. In the present work, titanium porous scaffolds were produced from TiH2 slurry by a replication sponge reactive sintering method, and coated with hydroxyapatite by the sol-gel process. The obtained structures were microstructurally and mechanically characterized. Their in vitro bioactivity was investigated by soaking in a simulated body fluid (SBF). Electrochemical characterization was also performed in order to evaluate the effect of coating on corrosion resistance. The scaffolds exhibit a three-dimensionally interconnected porous structure that can be mechanically and morphologically compared to trabecular bone. Their in vitro bioactivity suggests potential for osseous integration. Coating also improves corrosion resistance in physiologically saline environment.
引用
收藏
页码:451 / 457
页数:7
相关论文
共 26 条
  • [21] A bioactive titanium foam scaffold for bone repair
    Spoerke, ED
    Murray, NG
    Li, HL
    Brinson, LC
    Dunand, DC
    Stupp, SI
    [J]. ACTA BIOMATERIALIA, 2005, 1 (05) : 523 - 533
  • [22] Three-dimensional growth of differentiating MC3T3-E1 pre-osteoblasts on porous titanium scaffolds
    St-Pierre, JP
    Gauthier, M
    Lefebvre, LP
    Tabrizian, M
    [J]. BIOMATERIALS, 2005, 26 (35) : 7319 - 7328
  • [23] Mechanical properties and osteoconductivity of porous bioactive titanium
    Takemoto, M
    Fujibayashi, S
    Neo, M
    Suzuki, J
    Kokubo, T
    Nakamura, T
    [J]. BIOMATERIALS, 2005, 26 (30) : 6014 - 6023
  • [24] Corrosion behavior and surface characterization of titanium in solution containing fluoride and albumin
    Takemoto, S
    Hattori, M
    Yoshinari, M
    Kawada, E
    Oda, Y
    [J]. BIOMATERIALS, 2005, 26 (08) : 829 - 837
  • [25] THANARAISEL TV, 2004, TRENDS BIOMATER ARTI, V18, P9
  • [26] Processing and mechanical properties of autogenous titanium implant materials
    Wen, CE
    Yamada, Y
    Shimojima, K
    Chino, Y
    Asahina, T
    Mabuchi, M
    [J]. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2002, 13 (04) : 397 - 401