(Antibiotic-Resistant) E. coli in the Dutch-German Vecht Catchment-Monitoring and Modeling

被引:11
作者
van Heijnsbergen, Eri [1 ]
Niebaum, Gunnar [2 ]
Laemmchen, Volker [2 ]
Borneman, Alicia [1 ]
Leal, Lucia Hernandez [1 ]
Klasmeier, Joerg [2 ]
Schmitt, Heike [1 ,3 ]
机构
[1] Wetsus, European Ctr Excellence Sustainable Water Technol, NL-8911 MA Leeuwarden, Netherlands
[2] Osnabruck Univ, Inst Environm Syst Res, D-49076 Osnabruck, Germany
[3] Univ Utrecht, Inst Risk Assessment Sci, NL-3584 CM Utrecht, Netherlands
关键词
E; coli; ESBL-producing E. coli; carbapenemase-producing E. coli; geo-referenced modeling; microbial water quality; aquatic exposure assessment; CARBAPENEMASE-PRODUCING ENTEROBACTERIACEAE; WATER TREATMENT PLANTS; ESCHERICHIA-COLI; FECAL CONTAMINATION; MANURE APPLICATION; ASSESSMENT-TOOL; SURFACE-WATER; BACTERIA; RELEASE; FATE;
D O I
10.1021/acs.est.2c00218
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Fecally contaminated waters can be a source for human infections. We investigated the occurrence of fecal indicator bacteria (E. coli) and antibiotic-resistant E. coli, namely, extended spectrum beta-lactamase (ESBL)-producing E. coli (ESBL-EC) and carbapenemase-producing E. coli (CP-EC) in the Dutch-German transboundary catchment of the Vecht River. Over the course of one year, bacterial concentrations were monitored in wastewater treatment plant (WWTP) influents and effluents and in surface waters with and without WWTP influence. Subsequently, the GREAT-ER model was adopted for the prediction of (antibiotic-resistant) E. coli concentrations. The model was parametrized and evaluated for two distinct scenarios (average flow scenario, dry summer scenario). Statistical analysis of WWTP monitoring data revealed a significantly higher (factor 2) proportion of ESBL-EC among E. coli in German compared to Dutch WWTPs. CP-EC were present in 43% of influent samples. The modeling approach yielded spatially accurate descriptions of microbial concentrations for the average flow scenario. Predicted E. coli concentrations exceed the threshold value of the Bathing Water Directive for a good bathing water quality at less than 10% of potential swimming sites in both scenarios. During a single swimming event up to 61 CFU of ESBL-EC and less than 1 CFU of CP-EC could be taken up by ingestion.
引用
收藏
页码:15064 / 15073
页数:10
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