Cancer Surgery in the Elderly

被引:28
作者
Kowdley, Gopal C. [1 ]
Merchant, Nishant [1 ]
Richardson, James P. [2 ]
Somerville, Justin [1 ]
Gorospe, Myriam [3 ]
Cunningham, Steven C. [1 ]
机构
[1] St Agnes Hosp Ctr, Dept Surg, Baltimore, MD 21229 USA
[2] St Agnes Hosp Ctr, Dept Med, Baltimore, MD 21229 USA
[3] NIH, NIA, Lab Mol Biol & Immunol, Baltimore, MD 21224 USA
来源
SCIENTIFIC WORLD JOURNAL | 2012年
基金
美国国家卫生研究院;
关键词
COMPREHENSIVE GERIATRIC ASSESSMENT; PANCREATICO-BILIARY TUMORS; LUNG-CANCER; PROSTATE-CANCER; PREOPERATIVE ASSESSMENT; CYSTIC NEOPLASMS; ASSESSMENT ACGA; BREAST-CANCER; COLON-CANCER; OLDER WOMEN;
D O I
10.1100/2012/303852
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The proportions both of elderly patients in the world and of elderly patients with cancer are both increasing. In the evaluation of these patients, physiologic age, and not chronologic age, should be carefully considered in the decision-making process prior to both cancer screening and cancer treatment in an effort to avoid ageism. Many tools exist to help the practitioner determine the physiologic age of the patient, which allows for more appropriate and more individualized risk stratification, both in the pre- and postoperative periods as patients are evaluated for surgical treatments and monitored for surgical complications, respectively. During and after operations in the oncogeriatric populations, physiologic changes occuring that accompany aging include impaired stress response, increased senescence, and decreased immunity, all three of which impact the risk/benefit ratio associated with cancer surgery in the elderly.
引用
收藏
页数:9
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