The cAMP/Epac1/Rap1 pathway in pancreatic carcinoma

被引：30
作者：
Lorenz, Richard [1 ]
Aleksic, Tamara [2 ]
Wagner, Martin [1 ]
Adler, Guido [1 ]
Weber, Christoph K. [3 ]
机构：
[1] Univ Ulm, Dept Internal Med 1, D-7900 Ulm, Germany
[2] Weatherhall Inst Mol Med 1, Oxford, England
[3] Klin Sonnenhof, Dept Gastroenterol, Bern, Switzerland
来源：
PANCREAS | 2008年 / 37卷 / 01期
关键词：
D O I：
10.1097/MPA.0b013e318160748f
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：102 / 103
页数：2
相关论文
共 50 条
  • [41] Deletion of Rap1b, but not Rap1a or Epac1, Reduces Protein Kinase A-Mediated Thyroid Cancer
    Huk, Danielle J.
    Ashtekar, Amruta
    Magner, Alexa
    La Perle, Krista
    Kirschner, Lawrence S.
    [J]. THYROID, 2018, 28 (09) : 1153 - 1161
  • [42] Lipopolysaccharide stimulates Epac1-mediated Rap1/NF-κB pathway in Raw 264.7 murine macrophages
    Moon, Eun-Yi
    Pyo, Suhkneung
    [J]. IMMUNOLOGY LETTERS, 2007, 110 (02) : 121 - 125
  • [43] A novel interplay between Rap1, Epac and PKA regulates induction of angiogenesis
    Menon, Jyotsana
    Doebele, Robert C.
    Rosner, Marsha R.
    [J]. CANCER RESEARCH, 2011, 71
  • [44] Glucagon transiently stimulates mTORC1 by activation of an EPAC/Rap1 signaling axis
    Sunilkumar, Siddharth
    Kimball, Scot R.
    Dennis, Michael D.
    [J]. CELLULAR SIGNALLING, 2021, 84
  • [45] Expression of the cAMP Binding Protein EPAC1 in Thyroid Tumors and Growth Regulation of Thyroid Cells and Thyroid Carcinoma Cells by EPAC Proteins
    Broecker-Preuss, M.
    Baten, J.
    Sheu-Grabellus, S. -Y.
    Goerges, R.
    Bockisch, A.
    Schmid, K. W.
    Fuehrer, D.
    Mann, K.
    [J]. HORMONE AND METABOLIC RESEARCH, 2015, 47 (03) : 200 - 208
  • [46] A novel interplay between Rap1, Epac and PKA regulates induction of angiogenesis
    Menon, Jyotsana
    Doebele, Robert S.
    Rosner, Marsha Rich
    [J]. CLINICAL & EXPERIMENTAL METASTASIS, 2011, 28 (02) : 246 - 247
  • [47] Identification and Characterization of an Affimer Affinity Reagent for the Detection of the cAMP Sensor, EPAC1
    Buist, Hanna K.
    Luchowska-Stanska, Urszula
    van Basten, Boy
    Valli, Jessica
    Smith, Brian O.
    Baillie, George S.
    Rickman, Colin
    Ricketts, Bryon
    Davidson, Alex
    Hannam, Ryan
    Sunderland, Joanne
    Yarwood, Stephen J.
    [J]. CELLS, 2021, 10 (09)
  • [48] cAMP via Epac/Rap1 enhanced microvascular endothelial barrier functions by Rac1-mediated reorganization of adherens and tight junctions
    Peter, Dominik
    Spindler, Volker
    Waschke, Jens
    [J]. FASEB JOURNAL, 2010, 24
  • [49] Host Epac1 is required for cAMP-mediated invasion by Trypanosoma cruzi
    Musikant, Daniel
    Ferri, Gabriel
    Durante, Ignacio M.
    Buscaglia, Carlos A.
    Altschuler, Daniel L.
    Edreira, Martin M.
    [J]. MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2017, 211 : 67 - 70
  • [50] EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation
    M Huang
    S Anand
    E A Murphy
    J S Desgrosellier
    D G Stupack
    S J Shattil
    D D Schlaepfer
    D A Cheresh
    [J]. Oncogene, 2012, 31 : 2783 - 2793
12345