Structure, thermal stability and water solubility of (Tanshinone II-A)/(β-cyclodextrin) inclusion complex

被引:0
作者
Yang, SH [1 ]
Hu, M [1 ]
Shen, YL [1 ]
Ma, XY [1 ]
机构
[1] Lanzhou Univ, Dept Chem, Natl Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
关键词
tanshinone II-A; beta-cyclodextrin; inclusion complex; microwave irradiation;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The structure of the inclusion complex of tanshinone II-A and beta-cyclodextrin formed under microwave irradiation was studied by the UV, IR, and NMR spectroscopy. The association constant of the complex in water is 210 M-1, as determined from the double reciprocal curve by UV spectroscopy. The enhanced water solubility of the complex was found. Thermal studies proved the increased thermal stability of the inclusion complex.
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页码:53 / 61
页数:9
相关论文
共 15 条
[11]   Cyclodextrin drug carrier systems [J].
Uekama, K ;
Hirayama, F ;
Irie, T .
CHEMICAL REVIEWS, 1998, 98 (05) :2045-2076
[12]   INCREASED PODOPHYLLOTOXIN PRODUCTION IN PODOPHYLLUM-HEXANDRUM CELL-SUSPENSION CULTURES AFTER FEEDING CONIFERYL ALCOHOL AS A BETA-CYCLODEXTRIN COMPLEX [J].
WOERDENBAG, HJ ;
VANUDEN, W ;
FRIJLINK, HW ;
LERK, CF ;
PRAS, N ;
MALINGRE, TM .
PLANT CELL REPORTS, 1990, 9 (02) :97-100
[13]  
Yan XH, 2001, POL J CHEM, V75, P1297
[14]  
YAN XH, 2001, CHEM RES CHI U S, V17, P174
[15]  
陈亮, 1998, 波谱学杂志, V15, P243