From static to dynamic: escaping kinetic traps in hydrazone-based dynamic combinatorial libraries

被引：36

作者：

Beeren, Sophie R. ^{[1
]}

Pittelkow, Michael ^{[1
]}

Sanders, Jeremy K. M. ^{[1
]}

机构：

[1] Univ Cambridge, Univ Chem Lab, Cambridge CB2 1EW, England

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 26期

基金：

英国工程与自然科学研究理事会;

关键词：

NUCLEOPHILIC CATALYSIS; COVALENT CHEMISTRY; AMPLIFICATION; DISCOVERY; OLIGOMERS;

D O I：

10.1039/c1cc12268a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Thermodynamic control over kinetically-trapped mixtures of hydrazone-based macrocycles is achieved by addition of an aromatic monohydrazide to generate dynamic combinatorial libraries (DCLs) of linear and macrocyclic oligomers.

引用

页码：7359 / 7361

页数：3

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