Radiotherapeutic alternatives for previously irradiated recurrent gliomas

被引:65
作者
Combs, Stephanie E. [1 ]
Debus, Juergen [1 ]
Schulz-Ertner, Daniela [1 ]
机构
[1] Univ Heidelberg Hosp, Dept Radiat Oncol, D-69120 Heidelberg, Germany
关键词
D O I
10.1186/1471-2407-7-167
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Re-irradiation for recurrent gliomas has been discussed controversially in the past. This was mainly due to only marginal palliation while being associated with a high risk for side effects using conventional radiotherapy. With modern high-precision radiotherapy re-irradiation has become a more wide-spread, effective and well-tolerated treatment option. Besides external beam radiotherapy, a number of invasive and/or intraoperative radiation techniques have been evaluated in patients with recurrent gliomas. The present article is a review on the available methods in radiation oncology and summarizes results with respect to outcome and side effects in comparison to clinical results after neurosurgical resection or different chemotherapeutic approaches.
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页数:11
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