Differentiation of Intercalated Cells in the Kidney

被引：30

作者：

Al-Awqati, Qais ^{[1
]}

Gao, Xaio Bo

机构：

[1] Columbia Univ, Dept Med, Coll Phys & Surg, New York, NY 10027 USA

来源：

PHYSIOLOGY | 2011年 / 26卷 / 04期

关键词：

RENAL TUBULAR-ACIDOSIS; CIS-TRANS ISOMERASE; COLLECTING DUCT; EPITHELIAL-CELLS; TERMINAL DIFFERENTIATION; EXOCYTOTIC INSERTION; TRANSCRIPTION FACTOR; METABOLIC-ACIDOSIS; LUMINAL MEMBRANE; TURTLE-BLADDER;

D O I：

10.1152/physiol.00008.2011

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The intercalated cell of collecting ducts of the kidney is of two forms, the alpha form secretes acid, whereas the beta form secretes HCO3. Here, we review recent work that shows that the alpha form is derived from the beta form and that the pathway is mediated by an extracellular matrix protein called hensin/DMBT1.

引用

页码：266 / 272

页数：7

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