Molecularly imprinted high affinity nanoparticles for 4-ethylphenol sensing

被引：6

作者：

Garcia-Mutio, D. ^{[1
]}

Guerreiro, A. ^{[2
]}

Gomez-Caballero, A. ^{[1
]}

Gutierrez-Climente, R. ^{[1
]}

Piletsky, S. ^{[2
]}

Goicolea, M. A. ^{[1
]}

Barrio, R. J. ^{[1
]}

机构：

[1] Univ Basque Country UPV EHU, Fac Pharm, Dept Analyt Chem, Paseo Univ 7, Vitoria 01006, Spain

[2] Univ Leicester, Dept Chem, Leicester LE1 7RH, Leics, England

来源：

EUROSENSORS 2015 | 2015年 / 120卷

关键词：

4-ethylphenol; electrochemical sensor; molecularly imprinted nanoparticles; solid phase synthesis; POLYMER NANOPARTICLES;

D O I：

10.1016/j.proeng.2015.08.821

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A novel sensor for 4-ethylphenol (4EP) was developed based on molecularly imprinted nanoparticles produced via the solid phase imprinting method. The nanoparticles were immobilised on the surface of a gold electrode previously modified with a self assembled monolayer of lipoic acid coupled to EDC/NHS ((l-ethyl-34dimethylaminopropyl]carbodiimide)/Nhydroxysuccinimide). Each step of the process was characterised by electrochemical impedance spectroscopy and cyclic voltammetry. The electrode was used to selectively determine 4EP by differential pulse voltammetry; a quite remarkable sensitivity improvement was observed in the nanoparticle-modified electrode in reference to the non modified bare gold electrode. (C) 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-ric-nd/4.0/) Peer-review under responsibility of the organizing committee of EUROSENSORS

引用

页码：1132 / 1136

页数：5

共 9 条

[1] Electrochemical immunosensor modified with self-assembled monolayer of 11-mercaptoundecanoic acid on gold electrodes for detection of benzo[a]pyrene in water [J].