Towards In Vivo Tumor Detection Using Polarization and Wavelength Characteristics of Self-Assembled Gold Nanorods

被引：13
|
作者：
Hou, Ke [1 ]
Fixler, Dror [2 ,3 ]
Han, Bing [4 ]
Shi, Lin [1 ]
Feder, Idit [2 ,3 ]
Duadi, Hamootal [2 ,3 ]
Wang, Xiaoli [1 ]
Tang, Zhiyong [1 ]
机构：
[1] Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Nanosyst & Hierarchy Fabricat, Beijing 100190, Peoples R China
[2] Bar Ilan Univ, Fac Engn, IL-52900 Ramat Gan, Israel
[3] Bar Ilan Univ, Inst Nanotechnol & Adv Mat, IL-52900 Ramat Gan, Israel
[4] North China Elect Power Univ, Coll Environm Sci & Engn, 2 Beinong Rd, Changping Dist, Peoples R China
来源：
CHEMNANOMAT | 2017年 / 3卷 / 10期
基金：
中国国家自然科学基金;
关键词：
bioimaging; gold; nanorods; polarization; self-assembly; GROWTH;
D O I：
10.1002/cnma.201700157
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This work suggests a novel concept for sensing the back-reflected and absorbed light at two polarization states and at several wavelengths based on self-assembled gold nanorods (SGNs). While the SGNs are flowing in the bloodstream, the reflected light has a low degree of polarization at the specific wavelength. In comparison, when the SGNs are not moving, such as when the SGNs are located in a tumor, the reflected light has a high degree of polarization. Impressively, the SGNs structures further display a considerably improved contrast in the diffusion reflection (DR) system. Such characteristics provide a new strategy for possible in vivo detection of a tumor with enhanced resolution.
引用
收藏
页码：736 / 739
页数：4
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