Towards In Vivo Tumor Detection Using Polarization and Wavelength Characteristics of Self-Assembled Gold Nanorods

被引：13

作者：

Hou, Ke ^{[1
]}

Fixler, Dror ^{[2
,3
]}

Han, Bing ^{[4
]}

Shi, Lin ^{[1
]}

Feder, Idit ^{[2
,3
]}

Duadi, Hamootal ^{[2
,3
]}

Wang, Xiaoli ^{[1
]}

Tang, Zhiyong ^{[1
]}

机构：

[1] Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Nanosyst & Hierarchy Fabricat, Beijing 100190, Peoples R China

[2] Bar Ilan Univ, Fac Engn, IL-52900 Ramat Gan, Israel

[3] Bar Ilan Univ, Inst Nanotechnol & Adv Mat, IL-52900 Ramat Gan, Israel

[4] North China Elect Power Univ, Coll Environm Sci & Engn, 2 Beinong Rd, Changping Dist, Peoples R China

来源：

CHEMNANOMAT | 2017年 / 3卷 / 10期

基金：

中国国家自然科学基金;

关键词：

bioimaging; gold; nanorods; polarization; self-assembly; GROWTH;

D O I：

10.1002/cnma.201700157

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This work suggests a novel concept for sensing the back-reflected and absorbed light at two polarization states and at several wavelengths based on self-assembled gold nanorods (SGNs). While the SGNs are flowing in the bloodstream, the reflected light has a low degree of polarization at the specific wavelength. In comparison, when the SGNs are not moving, such as when the SGNs are located in a tumor, the reflected light has a high degree of polarization. Impressively, the SGNs structures further display a considerably improved contrast in the diffusion reflection (DR) system. Such characteristics provide a new strategy for possible in vivo detection of a tumor with enhanced resolution.

引用

页码：736 / 739

页数：4

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