Additive Effectiveness of Everolimus Plus Tamoxifen Therapy in Treatment of Encapsulating Peritoneal Sclerosis

被引：17

作者：

Huddam, Bulent ^{[1
]}

Azak, Alper ^{[1
]}

Kocak, Gulay ^{[1
]}

Basaran, Murat ^{[1
]}

Voyvoda, Nuray ^{[2
]}

Duranay, Murat ^{[1
]}

机构：

[1] Ankara Educ & Res Hosp, Dept Nephrol, Ankara, Turkey

[2] Acibadem Univ, Fac Med, Dept Radiol, Kocaeli, Turkey

来源：

RENAL FAILURE | 2012年 / 34卷 / 03期

关键词：

encapsulating peritoneal sclerosis; tamoxifen; everolimus; DIALYSIS; PATIENT; MULTICENTER;

D O I：

10.3109/0886022X.2011.647338

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Peritoneal dialysis (PD) is one of the commonly used choices of continuous renal replacement therapies. Peritoneal membrane is damaged by using solutions with lower biocompatibility, peritonitis episodes, and vintage of PD therapy. Encapsulating peritoneal sclerosis (EPS) is a rare complication of PD and is presented by progressive fibrosis of the peritoneum. Fibrous tissue entrapment of the intestine, leading to complete intestinal obstruction, is referred to as EPS, the most severe form of sclerosing peritonitis. EPS is irreversible fibrosis of the peritoneal membrane usually associated with high rates of morbidity and mortality. Preventive strategies are the best choice of treatment. Also there is no proven effective therapy for EPS; there are only small-sized trials. Herein we present a case of EPS who improved with everolimus plus tamoxifen therapy.

引用

页码：387 / 389

页数：3

共 17 条

[1] del Peso Gloria, 2003, Adv Perit Dial, V19, P32
[2] Duman Soner, 2008, Adv Perit Dial, V24, P104
[3] Eltoum MA, 2006, PERITON DIALYSIS INT, V26, P203
[4] Corticosteroid and tamoxifen therapy in sclerosing encapsulating peritonitis in a patient on continuous ambulatory peritoneal dialysis
Evrenkaya, TR
Atasoyu, EM
Unver, S
Basekim, C
Baloglu, H
Tulbek, MY
[J]. NEPHROLOGY DIALYSIS TRANSPLANTATION, 2004, 19 (09) : 2423 - 2424
[5] The potential of matrix metalloproteinase-2 as a marker of peritoneal injury, increased solute transport, or progression to encapsulating peritoneal sclerosis during peritoneal dialysis - a multicentre study in Japan
Hirahara, Ichiro
Inoue, Makoto
Okuda, Kousuke
Ando, Yasuhiro
Muto, Shigeaki
Kusano, Eiji
[J]. NEPHROLOGY DIALYSIS TRANSPLANTATION, 2007, 22 (02) : 560 - 567
[6] Kawanishi H, 2007, PERITON DIALYSIS INT, V27, pS289
[7] Tamoxifen is associated with lower mortality of encapsulating peritoneal sclerosis: results of the Dutch Multicentre EPS Study
Korte, Mario R.
Fieren, Marien W.
Sampimon, Denise E.
Lingsma, Hester F.
Weimar, Willem
Betjes, Michiel G. H.
[J]. NEPHROLOGY DIALYSIS TRANSPLANTATION, 2011, 26 (02) : 691 - 697
[8] Krediet RT, 2007, PERITON DIALYSIS INT, V27, pS35
[9] Sclerosing encapsulating peritonitis after orthotopic liver transplantation
Maguire, D
Srinivasan, P
O'Grady, J
Rela, M
Heaton, ND
[J]. AMERICAN JOURNAL OF SURGERY, 2001, 182 (02) : 151 - 154
[10] First use of tamoxifen in an HIV patient with encapsulating peritoneal sclerosis
Mesquita, M.
Guillaume, M. P.
Dratwa, M.
[J]. CLINICAL DRUG INVESTIGATION, 2007, 27 (10) : 727 - 729

← 1 2 →