Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds

被引:2
作者
Liu, Chongyang [1 ]
Gong, Zhaohua [1 ]
Huo, Zhaoyi [2 ]
Shen, Bangyu [3 ]
机构
[1] Shandong Inst Business & Technol, Sch Math & Informat Sci, Yantai 264005, Shandong, Peoples R China
[2] Dalian Univ Technol, Sch Energy & Power Engn, Dalian 116024, Liaoning, Peoples R China
[3] Huaiyin Normal Univ, Sch Math Sci, Huaian 223300, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
NONLINEAR IMPULSIVE SYSTEM; PARAMETER-IDENTIFICATION; KLEBSIELLA-PNEUMONIAE; OPTIMIZATION; GLYCEROL; 1,3-PROPANEDIOL; CULTURES;
D O I
10.1155/2012/245315
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
A nonlinear dynamical system, in which the feed rates of glycerol and alkali are taken as the control functions, is first proposed to formulate the fed-batch culture of 1,3-propanediol (1,3-PD) production. To maximize the 1,3-PD concentration at the terminal time, a constrained optimal control model is then presented. A solution approach is developed to seek the optimal feed rates based on control vector parametrization method and improved differential evolution algorithm. The proposed methodology yielded an increase by 32.17% of 1,3-PD concentration at the terminal time.
引用
收藏
页数:13
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