Endocrine therapy for metastatic solid pseudopapillary neoplasm of the pancreas: A case report

被引:6
作者
Kornietskaya, Anna [1 ]
Evdokimova, Sevindzh [1 ]
Kachmazov, Andrei [1 ]
Fedenko, Alexander [1 ]
Bolotina, Larisa [1 ]
Sidorov, Dmitriy [2 ]
Volchenko, Nadezhda [1 ]
Goeva, Natalia [1 ]
Govaleshko, Anastasia [1 ]
Kaprin, Andrey [1 ,3 ]
机构
[1] P Hertsen Moscow Oncol Res Inst, Branch Natl Med Res Radiol Ctr, Minist Hlth Russian Federat, Moscow, Russia
[2] City Clin Oncol Hosp 1, Moscow, Russia
[3] Peoples Friendship Univ Russia, Moscow, Russia
来源
FRONTIERS IN ONCOLOGY | 2022年 / 12卷
关键词
solid pseudopapillary neoplasm (SPN); pancreas; tamoxifen; endocrine therapy; case report; CYSTIC TUMOR; PAPILLARY; EXPERIENCE; MANAGEMENT; HAMOUDI;
D O I
10.3389/fonc.2022.970142
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Solid pseudopapillary neoplasm (SPN) of the pancreas is an extremely rare tumor, associated with favorable prognosis and long-term survival in patients with advanced disease. However, limited data exist on systemic therapy for such patients. Herein, we present a case of a young woman with a history of SPN, who progressed after multiple surgical resections and chemotherapy regimens. The immunohistochemistry (IHC) showed overexpression of estrogen receptors (ER) and progesterone receptors (PR) in tumor tissue. The patient started to receive tamoxifen and showed a durable response to endocrine therapy.
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页数:6
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