Interfacial enzymology:: The secreted phospholipase A2-paradigm

被引：340
作者：
Berg, OG
Gelb, MH
Tsai, MD
Jain, MK [1 ]
机构：
[1] Univ Delaware, Dept Chem & Biochem, Newark, DE 19716 USA
[2] Uppsala Univ, Evolutionary Biol Ctr, Uppsala, Sweden
[3] Univ Washington, Dept Chem, Seattle, WA 98195 USA
[4] Univ Washington, Dept Biochem, Seattle, WA 98195 USA
[5] Ohio State Univ, Dept Chem, Columbus, OH 43210 USA
来源：
CHEMICAL REVIEWS | 2001年 / 101卷 / 09期
关键词：
D O I：
10.1021/cr990139w
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Interfacial enzymology was investigated. Interfacial enzymes carry out the catalytic turnover within the two-dimensional constraints of the interface because that is where their substrates are found. Results showed that the effect of the interface on the two-dimensional ligand binding equilibrium is the basis for the allostery and the detailed balance constraint.
引用
收藏
页码：2613 / 2653
页数：41
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