Interfacial enzymology:: The secreted phospholipase A2-paradigm

被引：340

作者：

Berg, OG

Gelb, MH

Tsai, MD

Jain, MK ^{[1
]}

机构：

[1] Univ Delaware, Dept Chem & Biochem, Newark, DE 19716 USA

[2] Uppsala Univ, Evolutionary Biol Ctr, Uppsala, Sweden

[3] Univ Washington, Dept Chem, Seattle, WA 98195 USA

[4] Univ Washington, Dept Biochem, Seattle, WA 98195 USA

[5] Ohio State Univ, Dept Chem, Columbus, OH 43210 USA

来源：

CHEMICAL REVIEWS | 2001年 / 101卷 / 09期

关键词：

D O I：

10.1021/cr990139w

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Interfacial enzymology was investigated. Interfacial enzymes carry out the catalytic turnover within the two-dimensional constraints of the interface because that is where their substrates are found. Results showed that the effect of the interface on the two-dimensional ligand binding equilibrium is the basis for the allostery and the detailed balance constraint.

引用

页码：2613 / 2653

页数：41

共 339 条

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