Polypharmacology in Drug Discovery

被引:9
|
作者
Scotti, Luciana [1 ]
Scotti, Marcus T. [1 ]
机构
[1] Univ Fed Paraiba, Campus 1, BR-58051900 Joao Pessoa, PB, Brazil
关键词
DESIGN; OPPORTUNITIES; DERIVATIVES;
D O I
10.2174/1381612822999160405113658
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:3071 / 3072
页数:2
相关论文
共 50 条
  • [41] GES polypharmacology fingerprints: A novel and powerful drug repositioning tool
    Perez-Nueno, Violeta I.
    Karaboga, Arnaud S.
    Souchet, Michel
    Ritchie, Dave
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [42] Medicinal polypharmacology: Exploration and exploitation of the polypharmacolome in modern drug development
    Stefan, Sven Marcel
    Rafehi, Muhammad
    DRUG DEVELOPMENT RESEARCH, 2024, 85 (01)
  • [43] Predicting drug polypharmacology using secondary structure element information
    Koch, Oliver
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [44] Drug Effect Prediction by Polypharmacology-Based Interaction Profiling
    Simon, Zoltan
    Peragovics, Agnes
    Vigh-Smeller, Margit
    Csukly, Gabor
    Tombor, Laszlo
    Yang, Zhenhui
    Zahoranszky-Kohalmi, Gergely
    Vegner, Laszlo
    Jelinek, Balazs
    Hari, Peter
    Hetenyi, Csaba
    Bitter, Istvan
    Czobor, Pal
    Malnasi-Csizmadia, Andras
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2012, 52 (01) : 134 - 145
  • [45] PATHOME-Drug: a subpathway-based polypharmacology drug-repositioning method
    Nam, Seungyoon
    Lee, Sungyoung
    Park, Sungjin
    Lee, Jinhyuk
    Park, Aron
    Kim, Yon Hui
    Park, Taesung
    BIOINFORMATICS, 2022, 38 (02) : 444 - 452
  • [46] Multi-target-based polypharmacology prediction (mTPP): An approach using virtual screening and machine learning for multi-target drug discovery
    Liu, Kaiyang
    Chen, Xi
    Ren, Yue
    Liu, Chaoqun
    Lv, Tianyi
    Liu, Ya'nan
    Zhang, Yanling
    CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 368
  • [47] Drug discovery - Drug discovery: Affinity and beyond
    Janjic, N
    BIOPHARM-THE APPLIED TECHNOLOGIES OF BIOPHARMACEUTICAL DEVELOPMENT, 1998, 11 (02): : 28 - 28
  • [48] Applying polypharmacology approach for drug repurposing for SARS-CoV2
    Esther Jamir
    Himakshi Sarma
    Lipsa Priyadarsinee
    Selvaraman Nagamani
    Kikrusenuo Kiewhuo
    Anamika Singh Gaur
    Ravindra K Rawal
    Natarajan Arul Murugan
    Venkatesan Subramanian
    G Narahari Sastry
    Journal of Chemical Sciences, 2022, 134
  • [49] Applying polypharmacology approach for drug repurposing for SARS-CoV2
    Jamir, Esther
    Sarma, Himakshi
    Priyadarsinee, Lipsa
    Nagamani, Selvaraman
    Kiewhuo, Kikrusenuo
    Gaur, Anamika Singh
    Rawal, Ravindra K.
    Murugan, Natarajan Arul
    Subramanian, Venkatesan
    Sastry, G. Narahari
    JOURNAL OF CHEMICAL SCIENCES, 2022, 134 (02)
  • [50] Label-Free Cell Phenotypic Assays for Assessing Drug Polypharmacology
    Wang, Jixia
    Zhang, Xiuli
    Fang, Ye
    Liang, Xinmiao
    CURRENT PHARMACEUTICAL DESIGN, 2016, 22 (21) : 3190 - 3200