A Glimpse into Green Chemistry Practices in the Pharmaceutical Industry

被引：88

作者：

Sharma, Sudripet ^{[1
]}

Das, Jagattaran ^{[2
,3
]}

Braje, Wilfried M. ^{[4
]}

Dash, Ashutosh K. ^{[2
]}

Handa, Sachin ^{[1
]}

机构：

[1] Univ Louisville, Dept Chem, 2320 S Brook St, Louisville, KY 40292 USA

[2] Shoolini Univ, Sch Pharmaceut Sci, Solon, HP, India

[3] Baddi Univ Emerging Sci & Technol, Sch Pharm & Emerging Sci, Baddi, HP, India

[4] AbbVie Deutschland GmbH & Co KG, Med Chem, Neurosci Discovery Res, Knollstr, D-67061 Ludwigshafen, Germany

来源：

CHEMSUSCHEM | 2020年 / 13卷 / 11期

关键词：

catalysis; chemistry in water; cross-coupling; green chemistry; micellar catalysis; SUZUKI-MIYAURA COUPLINGS; AMIDE BOND FORMATION; CATALYZED C-N; ASYMMETRIC-SYNTHESIS; EFFICIENT SYNTHESIS; ORGANIC-SYNTHESIS; HECK REACTION; ARYL HALIDES; PALLADIUM CATALYSTS; GAMMA-VALEROLACTONE;

D O I：

10.1002/cssc.202000317

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this Minireview, the importance and implementation of green chemistry practices in the pharmaceutical industry are illustrated. With notable examples, some of the most important industrial organic transformations are discussed along with their applications in the synthesis of drug molecules. A brief comparison between traditional unsustainable methods and modern green methods is made to shed light on the economic and environmental benefits of greener methods. Finally, green chemistry practices in the pharmaceutical industries of India and China are also discussed.

引用

页码：2859 / 2875

页数：17

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