Antifungal Resistance Trends of Candida auris Clinical Isolates in New York and New Jersey from 2016 to 2020

被引：34

作者：

Kilburn, Shannon ^{[1
]}

Innes, Gabriel ^{[2
]}

Quinn, Monica ^{[1
]}

Southwick, Karen ^{[3
]}

Ostrowsky, Belinda ^{[4
]}

Greenko, Jane A. ^{[5
]}

Lutterloh, Emily ^{[1
,6
]}

Greeley, Rebecca ^{[2
]}

Magleby, Reed ^{[2
]}

Chaturvedi, Vishnu ^{[1
]}

Chaturvedi, Sudha ^{[1
,6
]}

机构：

[1] New York State Dept Hlth, Albany, NY 12202 USA

[2] New Jersey Dept Hlth, Trenton, NJ USA

[3] New York State Dept Hlth, New Rochelle, NY USA

[4] CDC, Ctr Dis Control & Prevent, Atlanta, GA 30333 USA

[5] New York State Dept Hlth, Cent Islip, NY USA

[6] State Univ Albany Sch Publ Hlth, Albany, NY 12222 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2022年 / 66卷 / 03期

关键词：

antifungals; Candida auris; minimum inhibitory concentration; epidemiological cutoff;

D O I：

10.1128/aac.02242-21

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to C. auris clinical isolates but not for New Jersey, highlighting the regional differences. About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to C. auris clinical isolates but not for New Jersey, highlighting the regional differences.

引用

页数：5

共 43 条

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CURRENT MEDICINAL CHEMISTRY, 2019, 26 (27) : 5108 - 5123
[42] Evaluation of a new T2 Magnetic Resonance assay for rapid detection of emergent fungal pathogen Candida auris on clinical skin swab samples
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Bentz, Meghan L.
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[43] Impact of the New Clinical Breaking Points Proposed by the Clinical and Laboratory Standards Institute (CLSI) in the Antifungal Susceptibility Profile of Clinical Strains Isolated from Invasive Bloodstream Candida Spp. Infections in Spain
Cisterna, R.
Telleria, O.
Hernaez, S.
Ezpeleta, G.
CLINICAL MEDICINE INSIGHTS-THERAPEUTICS, 2012, 4 : 19 - 27

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