Conjugate addition of silyl groups to beta-unsubstituted enones, & Si-to-OH conversion: A synthesis of (+/-)-lavandulol

被引：14
作者：
Fleming, I
Lee, D
机构：
[1] Department of Chemistry, Cambridge CB2 1EW, Lensfield Road
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 38期
关键词：
D O I：
10.1016/0040-4039(96)01519-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
TMS chloride raises the yield in the conjugate addition of silylcuprates and zincates to beta-unsubstituted enones, and Si-to-OH conversion is possible using the 2-methylbut-2-enyl(diphenyl)silyl group in the presence of highly nucleophilic alkenes. Both reactions are used in a synthesis of lavandulol. Copyright (C) 1996 Elsevier Science Ltd
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页码：6929 / 6930
页数：2
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