Determination of zearalenone in traditional Chinese medicinal plants and related products by HPLC-FLD

被引：35
作者：
Zhang, Xiaofei [1 ,2 ]
Liu, Wenkun [1 ,3 ]
Logrieco, Antonio F. [4 ]
Yang, Meihua [1 ]
Zhen Ou-yang [2 ]
Wang, Xiong [5 ]
Guo, Qi [5 ]
机构：
[1] Peking Union Med Coll, Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China
[2] Jiangsu Univ, Sch Pharm, Zhenjiang 212013, Peoples R China
[3] Jiangxi Univ Tradit Chinese Med, Sch Pharm, Nanchang 330004, Peoples R China
[4] CNR, Inst Sci Food Prod, ISPA, I-70126 Bari, Italy
[5] Clovertek Technol Grp Inc, Beijing 100044, Peoples R China
来源：
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT | 2011年 / 28卷 / 07期
关键词：
HPLC; LC/MS; affinity columns; quality assurance; mycotoxins; zearalenone; plants; PERFORMANCE LIQUID-CHROMATOGRAPHY; FUSARIUM MYCOTOXINS; ALPHA-ZEARALENOL; GAS-CHROMATOGRAPHY; BETA-ZEARALENOL; CORN; EXTRACTION; WHEAT; CEREAL; FEED;
D O I：
10.1080/19440049.2011.563429
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A HPLC-FLD method has been developed and validated for zearalenone (ZON) in 107 widely consumed Chinese medicinal herbs and related products collected from different regions of China. Samples were extracted with methanol/water (80 : 20, v/v), and the extracts were cleaned-up through immunoaffinity columns (IAC). ZON was quantified by HPLC with fluorescence detection. Recoveries from three different medicinal herbs spiked with ZON at levels ranging from 30 to 600 mu g kg(-1) were from 80.8 to 98.3%. The limit of detection was 9.5 mu g kg(-1), based on a signal-to-noise ratio of 3 : 1. Naturally occurring ZON was only found in coix seed medicinal herb (all nine samples), with levels ranging from 18.7 to 211.4 mu g kg(-1). Positive results were confirmed by UV spectrum and LC-ESI-MS/MS. This is the first report of ZON contamination of a Chinese medicinal herb.
引用
收藏
页码：885 / 893
页数：9
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