The validity of Acuros BV and TG-43 for high-dose-rate brachytherapy superficial mold treatments

被引:20
作者
Boman, Eeva L. [1 ,2 ,3 ]
Satherley, Thomas W. S. [1 ]
Schleich, Nanette [1 ]
Paterson, Dean B. [1 ]
Greig, Lynne [1 ]
Louwe, Rob J. W. [1 ]
机构
[1] Wellington Hosp, Blood & Canc Ctr, Wellington, New Zealand
[2] Tampere Univ Hosp, Dept Oncol, POB 2000, FI-33521 Tampere, Finland
[3] Tampere Univ Hosp, Dept Med Phys, Tampere, Finland
关键词
HDR brachytherapy; Surface mold; Skin treatment; Acuros BV; TG-43; Film dosimetry; EQUIVALENT PHANTOM MATERIALS; IR-192; BRACHYTHERAPY; WATER-EQUIVALENT; SKIN BRACHYTHERAPY; DOSIMETRY; AAPM; APPLICATORS; SCATTER; PHOTON; CS-137;
D O I
10.1016/j.brachy.2017.08.010
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PURPOSE: The purpose of this work is to validate the Acuros BV dose calculation algorithm for high-dose-rate (HDR) brachytherapy superficial mold treatments in the absence of full scatter conditions and compare this with TG-43 dose calculations. We also investigate the impact of additional back scatter material (bolus) applied above surface molds to the dose distributions under the mold. METHODS AND MATERIALS: The absorbed dose at various depths was compared for simulations performed using either TG-43 or Acuros BV dose calculations. Parameter variations included treatment area, thickness of the bolus, and surface shape (flat or spherical). Film measurements were carried out in a flat phantom. RESULTS: Acuros BV calculations and film measurements agreed within 1.5% but were up to 15% lower than TG-43 dose calculations when no bolus was applied above the treatment catheters. The difference in dose at the prescription depth (1 cm below the central catheter) increased with increasing treatment area: 3.3% difference for a 3 x 3.5 cm(2) source loading area, 7.4% for 8 x 9 cm(2), and 13.4% for 18 x 19 cm(2). The dose overestimation of the TG-43 model decreased when bolus was added above the treatment catheters. CONCLUSIONS: The TG-43 dosimetry formalism cannot model surface mold treatments in the absence of full scatter conditions within 5% for loading areas larger than approximately 5 x 5 cm(2). The TG-43 model results in an overestimation of the delivered dose, which increases with treatment area. This confirms the need for model-based dose calculation algorithms as discussed in TG-186. (C) 2017 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:1280 / 1288
页数:9
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